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protein O-fucosyltransferase 2

Summary

Gene Symbol

POFUT2

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 449505
KEGG Gene ID: ptr:449505
PubChem: 449505

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Fucose metabolism
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Signal
Transferase

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7CCI4	Peptide-O-fucosyltransferase 2
Q6EV56	Peptide-O-fucosyltransferase 2
A0A663D7E9	Peptide-O-fucosyltransferase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein O-linked fucosylation	IEA	30032202
fucose metabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

glycosylation [inference]

fucosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation [inference]

protein O-linked fucosylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi apparatus
endoplasmic reticulum

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
peptide-O-fucosyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

peptide-O-fucosyltransferase activity

catalytic activity, acting on a protein [inference]

peptide-O-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Hominidae
Group Name: GDP-fucose protein O-fucosyltransferase

Displaying entries **1 - 10** of 11 in total

1

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Gene Ontology
fucose metabolic process
fucosylation
fucosyltransferase activity
mesoderm formation
peptide-O-fucosyltransferase activity
positive regulation of protein folding
protein O-linked fucosylation
regulation of epithelial to mesenchymal transition
regulation of gene expression
regulation of secretion

Displaying **all 2** entries
InterPro
GDP-fucose protein O-fucosyltransferase 2-like
GDP-fucose protein O-fucosyltransferase

KEGG BRITE Database

Orthology

K03691

Name

peptide-O-fucosyltransferase [EC:2.4.1.221]

References

11524432

Rhea

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

GDP-β-L-fucose

H⁺ + GDP

Enzyme

2.4.1.221

PMID

Ortholog

Displaying **all 5** entries
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23275	9606_0:001ab4
Pongo abelii	100454664	9601_0:004ee5
Pan paniscus	100982903	9597_0:005246
Gorilla gorilla gorilla	101147854	9595_0:005467
Pongo pygmaeus	129022447	9600_0:004eda

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024