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BPI fold containing family A member 1

Summary

Gene Symbol

BPIFA1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 449524
PubChem: 449524

Annotation

Keyword

Antibiotic
Disulfide bond
Glycoprotein
Innate immunity
Lipid-binding
Reference proteome
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
K7GS01	Palate lung and nasal epithelium clone protein
Q5XW65	Lung and nasal epithelium carcinoma-associated protein Palate lung and nasal epithelium clone protein
A0A8D1D3G3	Palate lung and nasal epithelium clone protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
surfactant homeostasis
antimicrobial humoral immune response mediated by antimicrobial peptide	IEA	30032202
regulation of sodium ion transmembrane transport

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

chemical homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

immune response [inference]

immune response in gut-associated lymphoid tissue [inference]

immune response in nasopharyngeal-associated lymphoid tissue

humoral immune response [inference]

antimicrobial humoral response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

antibacterial humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

antibacterial humoral response

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

regulation of sodium ion transmembrane transport

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

regulation of biological process involved in symbiotic interaction [inference]

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport

negative regulation of cellular process [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of biological quality [inference]

regulation of body fluid levels [inference]

multicellular organismal-level water homeostasis

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
lipid binding	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

BPI fold-containing family A member 1

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
immune response in nasopharyngeal-associated lymphoid tissue
lipid binding
negative regulation of single-species biofilm formation in or on host organism

Displaying **all 2** entries
InterPro
Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-binding serum glycoprotein, N-terminal

Ortholog

Displaying entries **41 - 50** of 63 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Macaca nemestrina	105496214		MACNE13776
Mandrillus leucophaeus	105539462		MANLE18393
Cercocebus atys	105582274		CERAT03403
Aotus nancymaae	105719045		AOTNA05116
Propithecus coquereli	105827549		PROCO14211
Dipodomys ordii	105981490		DIPOR03612
Rhinopithecus bieti	108537004		RHIBE31004
Bos indicus	109567364	9915_0:0026a6
Vulpes vulpes	112928271		VULVU22930
Bos indicus x Bos taurus	113903123	30522_0:0026d1