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phospholipase A2 group XV

Summary

Gene Symbol

PLA2G15

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 454188
KEGG Gene ID: ptr:454188
PubChem: 454188

Annotation

Keyword

Hydrolase
Membrane
Reference proteome
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
H2QBD9	1-O-acylceramide synthase LCAT-like lysophospholipase Lysophospholipase 3 Lysosomal phospholipase A2 Phospholipase A2 group XV
A0A6D2WA35	1-O-acylceramide synthase LCAT-like lysophospholipase Lysophospholipase 3 Lysosomal phospholipase A2 Phospholipase A2 group XV

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ceramide metabolic process	IEA	30032202
phosphatidylcholine metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

ceramide metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phosphatidylcholine metabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phosphatidylcholine metabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

ceramide metabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylcholine metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
lysosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
O-acyltransferase activity	IEA	22301074 30032202
calcium-independent phospholipase A2 activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase A2 activity [inference]

calcium-independent phospholipase A2 activity

carboxylic ester hydrolase activity [inference]

phospholipase A2 activity [inference]

calcium-independent phospholipase A2 activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

phospholipase A2 group XV

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying entries **1 - 10** of 14 in total

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Gene Ontology
O-acyltransferase activity
acylglycerol O-acyltransferase activity
calcium-independent phospholipase A2 activity
ceramide metabolic process
diacylglycerol biosynthetic process
hydrolase activity
lipid metabolic process
phosphatidylcholine catabolic process
phosphatidylcholine metabolic process
phosphatidylethanolamine catabolic process

Displaying **all 2** entries
InterPro
Alpha/Beta hydrolase fold
Lecithin

KEGG BRITE Database

Orthology

K06129

Name

lysophospholipase III [EC:3.1.1.5]

References

10092508

Rhea

RHEA:15177

H₂O + a 1-acyl-sn-glycero-3-phosphocholine

H⁺ + sn-glycerol 3-phosphocholine + a fatty acid

Enzyme

3.1.1.5

PMID

RHEA:36231

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

9442064

RHEA:18689

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 2-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.32

PMID

RHEA:15801

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	23659	HUMAN29250
Mus musculus	192654	MOUSE57741
Bos taurus	282271	BOVIN10673
Rattus norvegicus	361401	RATNO14504
Canis lupus familiaris	403403	CANLF16022
Macaca mulatta	702619	MACMU26106
Monodelphis domestica	100022408	MONDO05138
Pongo abelii	100172651	PONAB11201
Ciona intestinalis	100178412	CIOIN13503
Salmo salar	100194817	SALSA11149

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Acknowledgements