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melatonin receptor 1A

Summary

Gene Symbol

MTNR1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

4543

PubChem

4543

Alliance of Genome Resources

HGNC:7463

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P48039

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	9645677
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	10531408
mating behavior	TAS	7946354
circadian rhythm	TAS	9645677

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

reproductive process [inference]

reproductive behavior [inference]

mating behavior

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

mating behavior

rhythmic process [inference]

circadian rhythm

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	10531408
plasma membrane	IBA
receptor complex	IDA	10531408

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IBA
protein binding	IPI	17215244 20859254 26514267 28298427 32296183
melatonin receptor activity	IDA	10531408
hormone binding	IPI	10531408
organic cyclic compound binding

GO Hierarchy

molecular function

binding [inference]

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

melatonin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

g-protein coupled receptor moody

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	187	WB:WBGene00020319
Xenopus tropicalis	4543	Xenbase:XB-GENE-985295
Drosophila melanogaster	4544	FB:FBgn0025631
Xenopus tropicalis	14765	Xenbase:XB-GENE-985295
Mus musculus	17773	Xenbase:XB-GENE-985295	MOUSE57646
Danio rerio	30667	Xenbase:XB-GENE-985295	DANRE17503
Drosophila melanogaster	30668	FB:FBgn0025631
Drosophila melanogaster	80910	FB:FBgn0025631
Rattus norvegicus	114211		RATNO10625
Xenopus tropicalis	140439	Xenbase:XB-GENE-985295