GlyCosmos Portal

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GO Term	Evidence Code	PMID
DNA N-glycosylase activity	TAS
MutLbeta complex binding	IDA	11801590
adenine/guanine mispair binding	IBA
4 iron, 4 sulfur cluster binding	IEA
MutSalpha complex binding	IDA	11801590

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

mismatch repair complex binding [inference]

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding [inference]

oxidized DNA binding [inference]

oxidized purine DNA binding

double-stranded DNA binding [inference]

mismatched DNA binding [inference]

adenine/guanine mispair binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **11 - 20** of **150** in total

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DO ID	Disease Name	Source
DOID:0080199	colorectal carcinoma	DisGeNET
DOID:0080409	familial adenomatous polyposis 1	DisGeNET DisGeNET DisGeNET
DOID:0080410	familial adenomatous polyposis 2	DisGeNET Alliance of Genome Resources
DOID:0090103	Huntington's disease-like 1	DisGeNET
DOID:0090104	Huntington's disease-like 2	DisGeNET
DOID:0110892	inflammatory bowel disease 1	DisGeNET
DOID:0111414	trichohepatoenteric syndrome	DisGeNET
DOID:0111415	trichohepatoenteric syndrome 1	DisGeNET
DOID:10283	prostate cancer	DisGeNET DisGeNET
DOID:10286	prostate carcinoma	DisGeNET DisGeNET

The Human Phenotype Ontology

Displaying entries **21 - 30** of 61 in total

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HPO ID	HPO Term
HP:0002027	Abdominal pain
HP:0002076	Migraine
HP:0002167	Abnormality of speech or vocalization
HP:0002239	Gastrointestinal hemorrhage
HP:0002354	Memory impairment
HP:0002376	Developmental regression
HP:0002516	Increased intracranial pressure
HP:0002671	Basal cell carcinoma
HP:0002893	Pituitary adenoma
HP:0002894	Neoplasm of the pancreas

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:613659	gastric cancer
ORPHA:440437	familial colorectal cancer type X
ORPHA:247798	familial adenomatous polyposis 2
OMIM:608456	familial adenomatous polyposis 2

PubChem Disease

GHR Health Conditions

Familial adenomatous polyposis

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **21 - 30** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Mandrillus leucophaeus	105555099	MANLE10203
Gorilla gorilla gorilla	101149779	GORGO21092
Pan paniscus	100991248	PANPA01224
Pan troglodytes	456539	PANTR20933
Pongo abelii	100458483	PONAB20057
Ursus americanus	123793764	URSAM23579
Mustela putorius furo	101689944	MUSPF18175
Felis catus	101089880	FELCA21167
Panthera leo	122226919	PANLE10194
Tursiops truncatus	117314463	TURTR06657