GlyCosmos Portal

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
DNA N-glycosylase activity	TAS
MutLbeta complex binding	IDA	11801590
adenine/guanine mispair binding	IBA
4 iron, 4 sulfur cluster binding	IEA
MutSalpha complex binding	IDA	11801590

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

oxidized base lesion DNA N-glycosylase activity [inference]

oxidized purine nucleobase lesion DNA N-glycosylase activity [inference]

8-oxo-7,8-dihydroguanine DNA N-glycosylase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

mismatch repair complex binding [inference]

metal cluster binding [inference]

iron-sulfur cluster binding [inference]

4 iron, 4 sulfur cluster binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding [inference]

oxidized DNA binding [inference]

oxidized purine DNA binding

double-stranded DNA binding [inference]

mismatched DNA binding [inference]

adenine/guanine mispair binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **41 - 50** of **150** in total

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DO ID	Disease Name	Source
DOID:1612	breast cancer	DisGeNET DisGeNET DisGeNET
DOID:3620	central nervous system cancer	DisGeNET
DOID:162	cancer	DisGeNET DisGeNET DisGeNET
DOID:169	neuroendocrine tumor	DisGeNET
DOID:1781	thyroid cancer	DisGeNET DisGeNET
DOID:1793	pancreatic cancer	DisGeNET
DOID:1799	islet cell tumor	DisGeNET
DOID:1800	neuroendocrine carcinoma	DisGeNET
DOID:1837	diabetic ketoacidosis	DisGeNET
DOID:1909	melanoma	DisGeNET

The Human Phenotype Ontology

Displaying entries **11 - 20** of 61 in total

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HPO ID	HPO Term
HP:0001260	Dysarthria
HP:0001276	Hypertonia
HP:0001288	Gait disturbance
HP:0001371	Flexion contracture
HP:0001402	Hepatocellular carcinoma
HP:0001442	Typified by somatic mosaicism
HP:0001824	Weight loss
HP:0002017	Nausea and vomiting
HP:0002019	Constipation
HP:0002024	Malabsorption

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:613659	gastric cancer
ORPHA:440437	familial colorectal cancer type X
ORPHA:247798	familial adenomatous polyposis 2
OMIM:608456	familial adenomatous polyposis 2

PubChem Disease

GHR Health Conditions

Familial adenomatous polyposis

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **31 - 40** of 63 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Balaenoptera musculus	118896659		BALMU22919
Loxodonta africana	100672454		LOXAF09311
Bos taurus	513051		BOVIN27071
Ovis aries	101119344		SHEEP00254
Oryctolagus cuniculus	100344165		RABIT03973
Cricetulus griseus	100752384		CRIGR03305
Mus musculus	70603	MGI:1917853	MOUSE41009
Rattus norvegicus	170841	RGD:620045	RATNO32646
Cyprinodon variegatus	107081949		CYPVA03758
Ursus maritimus	103670779		URSMA15009