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Submissions

mevalonate diphosphate decarboxylase

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

4597

PubChem

4597

Alliance of Genome Resources

HGNC:7529

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Cholesterol biosynthesis
Cytoplasm
Disease variant
Lyase
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P53602	Mevalonate (diphospho)decarboxylase Mevalonate pyrophosphate decarboxylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	9270019
cholesterol biosynthetic process	IEA NAS	14680974
isopentenyl diphosphate biosynthetic process, mevalonate pathway	IBA
isoprenoid biosynthetic process	IDA	11792727 14680974

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
peroxisome	IDA	14972328
cytosol	IBA IDA TAS	14972328

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

microbody [inference]

peroxisome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
diphosphomevalonate decarboxylase activity	IBA IDA	11792727 14680974
Hsp70 protein binding	IPI	12646231
ATP binding	IEA
protein homodimerization activity	IDA	8626466

GO Hierarchy

molecular function

catalytic activity [inference]

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

diphosphomevalonate decarboxylase activity

binding [inference]

protein binding [inference]

heat shock protein binding [inference]

Hsp70 protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding [inference]

Hsp70 protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

diphosphomevalonate decarboxylase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 10** entries
Gene Ontology
ATP binding
carboxy-lyase activity
diphosphomevalonate decarboxylase activity
isopentenyl diphosphate biosynthetic process, mevalonate pathway
lipid metabolic process
lyase activity
nucleotide binding
steroid biosynthetic process
steroid metabolic process
sterol biosynthetic process

Displaying **all 7** entries
InterPro
Diphosphomevalonate decarboxylase
Diphosphomevalonate/phosphomevalonate decarboxylase
GHMP kinase N-terminal domain
GHMP kinase, C-terminal domain superfamily
Mvd1, C-terminal
Ribosomal protein uS5 domain 2-type superfamily
Small ribosomal subunit protein uS5 domain 2-type fold, subgroup

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3805	porokeratosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	32520		FB:FBgn0030683
Rattus norvegicus	81726		RGD:621292
Caenorhabditis elegans	175078		WB:WBGene00012984
Mus musculus	192156		MGI:2179327	MOUSE59012
Xenopus tropicalis	394871		Xenbase:XB-GENE-975218
Pan troglodytes	468069	9598_0:003fc2		PANTR13061
Canis lupus familiaris	489663			CANLF15865
Danio rerio	492781		ZFIN:ZDB-GENE-041114-127	DANRE13993
Bos taurus	509958			BOVIN10298
Macaca mulatta	696865			MACMU26760

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements