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mevalonate kinase

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

4598

PubChem

4598

Alliance of Genome Resources

HGNC:7530

Annotation

Keyword

3D-structure
ATP-binding
Cataract
Cholesterol biosynthesis
Cytoplasm
Disease variant
Kinase
Magnesium
Metal-binding
Peroxisome
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B7Z301
B2RDU6
Q03426
F5H8H2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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Last »
GO Term	Evidence Code	PMID
cholesterol biosynthetic process	IDA	1377680
cholesterol biosynthetic process	IBA
isoprenoid biosynthetic process	IDA	14680974 14730012
phosphorylation
isopentenyl diphosphate biosynthetic process, mevalonate pathway	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorylation

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

phosphorylation

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

cellular biosynthetic process [inference]

isoprenoid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isopentenyl diphosphate metabolic process [inference]

isopentenyl diphosphate biosynthetic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

isoprenoid biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process [inference]

isopentenyl diphosphate biosynthetic process, mevalonate pathway

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

negative regulation of response to stimulus [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

negative regulation of response to external stimulus [inference]

negative regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of inflammatory response

regulation of inflammatory response [inference]

negative regulation of inflammatory response

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
peroxisome	ISS
peroxisome	IDA	14730012
cytosol	TAS
cytosol	IDA	14730012
cytosol	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

microbody [inference]

peroxisome

intracellular organelle [inference]

intracellular membrane-bounded organelle

microbody [inference]

peroxisome

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	ISS
mevalonate kinase activity	IDA	1377680 14680974 14730012 18302342 9325256
mevalonate kinase activity	IMP	10369261
mevalonate kinase activity	IBA
protein binding	IPI	21044950 32296183

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

mevalonate kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

mevalonate kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mevalonate kinase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying entries **1 - 10** of 13 in total

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Gene Ontology
ATP binding
cholesterol biosynthetic process
ergosterol biosynthetic process
isopentenyl diphosphate biosynthetic process, mevalonate pathway
kinase activity
lipid metabolic process
mevalonate kinase activity
nucleotide binding
phosphorylation
steroid biosynthetic process

Displaying **all 7** entries
InterPro
GHMP kinase N-terminal domain
GHMP kinase, ATP-binding, conserved site
GHMP kinase, C-terminal domain superfamily
GHMP kinase, C-terminal domain
Mevalonate kinase
Ribosomal protein uS5 domain 2-type superfamily
Small ribosomal subunit protein uS5 domain 2-type fold, subgroup

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050452	mevalonic aciduria	Alliance of Genome Resources
DOID:0081450	hyperimmunoglobulinemia D periodic fever syndrome	Alliance of Genome Resources
DOID:3146	lipid metabolism disorder	Alliance of Genome Resources
DOID:3805	porokeratosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	4598	Xenbase:XB-GENE-998892
Mus musculus	17855		MOUSE45223
Rattus norvegicus	81727		RATNO05734
Pan troglodytes	467175		PANTR06849
Danio rerio	492477		DANRE35702
Bos taurus	505792		BOVIN09684
Macaca mulatta	707645		MACMU03455
Monodelphis domestica	100016213		MONDO19044
Equus caballus	100066619		HORSE41662
Sus scrofa	100152230		PIGXX07017

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements