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transketolase

Summary

Gene Symbol

TKT

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 460443
KEGG Gene ID: ptr:460443
PubChem: 460443

Annotation

Keyword

Acetylation
Calcium
Isopeptide bond
Magnesium
Metal-binding
Phosphoprotein
Reference proteome
Thiamine pyrophosphate
Transferase
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5R1W6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
pentose-phosphate shunt, non-oxidative branch	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

generation of precursor metabolites and energy [inference]

pentose-phosphate shunt, non-oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organic substance metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

carbohydrate derivative metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

generation of precursor metabolites and energy [inference]

pentose-phosphate shunt, non-oxidative branch

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

organophosphate metabolic process [inference]

glyceraldehyde-3-phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

ribose phosphate metabolic process [inference]

pentose-phosphate shunt, non-oxidative branch

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
extracellular exosome	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
transketolase activity	IEA	30032202
thiamine pyrophosphate binding	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transketolase or transaldolase activity [inference]

transketolase activity

binding [inference]

small molecule binding [inference]

vitamin binding [inference]

thiamine pyrophosphate binding

quaternary ammonium group binding [inference]

thiamine pyrophosphate binding

heterocyclic compound binding [inference]

thiamine pyrophosphate binding

ion binding [inference]

anion binding [inference]

thiamine pyrophosphate binding

cation binding [inference]

thiamine pyrophosphate binding

organic cyclic compound binding [inference]

thiamine pyrophosphate binding

sulfur compound binding [inference]

thiamine pyrophosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

transketolase

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
catalytic activity
metal ion binding
pentose-phosphate shunt, non-oxidative branch
thiamine pyrophosphate binding
transferase activity
transketolase activity

Displaying **all 7** entries
InterPro
Thiamin diphosphate-binding fold
Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
Transketolase binding site
Transketolase conserved site
Transketolase, C-terminal domain
Transketolase, N-terminal
Transketolase-like, pyrimidine-binding domain

KEGG BRITE Database

Orthology

K00615

Name

transketolase [EC:2.2.1.1]

References

8419340

Rhea

D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate

D-xylulose 5-phosphate + aldehydo-D-ribose 5-phosphate

Enzyme

2.2.1.1

PMID

D-erythrose 4-phosphate + D-xylulose 5-phosphate

β-D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate

Enzyme

2.2.1.1

Ortholog

Displaying entries **41 - 50** of 92 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Haplochromis burtoni	102293420			HAPBU21147
Latimeria chalumnae	102356292			LATCH15672
Myotis lucifugus	102432222			MYOLU06322
Pelodiscus sinensis	102446618			PELSI13882
Neolamprologus brichardi	102792936			NEOBR05438
Astyanax mexicanus	103045188			ASTMX02108
Poecilia formosa	103156031			POEFO21344
Callorhinchus milii	103185044			CALMI31270
Chlorocebus sabaeus	103227756			CHLSB10445
Carlito syrichta	103268098			CARSF25650

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Last updated: December 9, 2024