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ectonucleotide pyrophosphatase/phosphodiesterase 3

Summary

Gene Symbol

ENPP3

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 463000
KEGG Gene ID: ptr:463000
PubChem: 463000

Annotation

Keyword

Disulfide bond
Metal-binding
Reference proteome
Secreted
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8PT67	Phosphodiesterase I beta Phosphodiesterase I/nucleotide pyrophosphatase 3
A0A6D2WP60	Phosphodiesterase I beta Phosphodiesterase I/nucleotide pyrophosphatase 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
nucleoside triphosphate catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside triphosphate metabolic process [inference]

nucleoside triphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside triphosphate catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA	22301074
nucleic acid binding	IEA	22301074
nucleoside triphosphate diphosphatase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

nucleoside triphosphate diphosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K01513

Name

ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]

References

Rhea

RHEA:29395

H₂O + UTP

H⁺ + diphosphate + UMP

Enzyme

PMID

RHEA:10248

H₂O + dUTP

H⁺ + dUMP + diphosphate

Enzyme

PMID

RHEA:28362

H₂O + dGTP

H⁺ + diphosphate + dGMP

Enzyme

3.6.1.9

PMID

RHEA:27762

H₂O + CTP

H⁺ + diphosphate + CMP

Enzyme

PMID

RHEA:22636

H₂O + dCTP

H⁺ + diphosphate + dCMP

Enzyme

PMID

RHEA:28610

H₂O + XTP

H⁺ + diphosphate + XMP

Enzyme

PMID

RHEA:28534

H₂O + dTTP

H⁺ + diphosphate + dTMP

Enzyme

3.6.1.9

PMID

RHEA:44644

H₂O + a 2'-deoxyribonucleoside 5'-triphosphate

H⁺ + diphosphate + a 2'-deoxyribonucleoside 5'-phosphate

Enzyme

3.6.1.9

PMID

12218018

RHEA:28342

H₂O + dITP

H⁺ + diphosphate + dIMP

Enzyme

PMID

RHEA:29391

H₂O + GTP

H⁺ + diphosphate + GMP

Enzyme

PMID

12218018

RHEA:28334

H₂O + dATP

H⁺ + diphosphate + dAMP

Enzyme

3.6.1.9

PMID

RHEA:29399

H₂O + ITP

H⁺ + diphosphate + IMP

Enzyme

PMID

RHEA:14245

H₂O + ATP

H⁺ + diphosphate + AMP

Enzyme

PMID

12218018

RHEA:23996

H₂O + a ribonucleoside 5'-triphosphate

H⁺ + diphosphate + a ribonucleoside 5'-phosphate

Enzyme

3.6.1.9

PMID

12218018

Ortholog

Displaying entries **41 - 50** of 61 in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113898426	BOBOX27496
Vicugna pacos	102537612	VICPA06341
Otolemur garnettii	100958111	OTOGA18712
Chinchilla lanigera	102019951	CHILA09962
Aotus nancymaae	105721307	AOTNA26471
Phascolarctos cinereus	110208874	PHACI29609
Saimiri boliviensis boliviensis	101038670	SAIBB20610
Jaculus jaculus	101599711	JACJA02286
Myotis lucifugus	102442736	MYOLU02250
Rhinolophus ferrumequinum	117020880	RHIFE10690

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Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements