GlyCosmos Portal

Displaying **all 4** entries
GO Term	Evidence Code	PMID
procollagen-lysine 5-dioxygenase activity	IEA	22301074 30032202
procollagen glucosyltransferase activity	IEA	30032202
iron ion binding	IEA	22301074
L-ascorbic acid binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

procollagen glucosyltransferase activity

catalytic activity, acting on a protein [inference]

procollagen glucosyltransferase activity

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

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Gene Ontology
L-ascorbic acid binding
basement membrane assembly
collagen fibril organization
collagen metabolic process
dioxygenase activity
endothelial cell morphogenesis
epidermis morphogenesis
hydroxylysine biosynthetic process
in utero embryonic development
iron ion binding

Displaying **all 5** entries
InterPro
Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain
Nucleotide-diphospho-sugar transferases
Oxoglutarate/iron-dependent dioxygenase
Procollagen-lysine 5-dioxygenase, conserved site
Prolyl 4-hydroxylase, alpha subunit

KEGG BRITE Database

Orthology

K13646

Name

lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]

References

Rhea

RHEA:16569

O₂ + 2-oxoglutarate

CO₂ + succinate

Enzyme

1.14.11.4

PMID

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	8985	9606_1:0021b6	HUMAN90460
Mus musculus	26433		MOUSE47276
Rattus norvegicus	288583		RATNO05275
Canis lupus familiaris	479730		CANLF16186
Bos taurus	514996		BOVIN20831
Danio rerio	556077		DANRE24743
Macaca mulatta	714283		MACMU31302
Monodelphis domestica	100017782		MONDO11120
Equus caballus	100059479		HORSE06663
Ornithorhynchus anatinus	100086224		ORNAN31667

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements