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aldehyde dehydrogenase 6 family member A1

Summary

Gene Symbol

ALDH6A1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 467506
KEGG Gene ID: ptr:467506
PubChem: 467506

Annotation

Keyword

Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6D2WL42
K7AKS9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
thymine catabolic process	IEA	30032202
valine catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity	IEA	22301074 30032202
malonate-semialdehyde dehydrogenase (acetylating) activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

methylmalonate-semialdehyde dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
brown fat cell differentiation
malonate-semialdehyde dehydrogenase (acetylating) activity
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity
thymine catabolic process
valine catabolic process

Displaying **all 6** entries
InterPro
Aldehyde dehydrogenase domain
Aldehyde dehydrogenase, C-terminal
Aldehyde dehydrogenase, N-terminal
Aldehyde dehydrogenase, cysteine active site
Aldehyde/histidinol dehydrogenase
Methylmalonate-semialdehyde dehydrogenase

KEGG BRITE Database

Orthology

K00140

Name

malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]

References

Rhea

H₂O + 3-oxopropanoate + CoA + NAD⁺

H⁺ + hydrogencarbonate + acetyl-CoA + NADH

Enzyme

1.2.1.27

PMID

16332250

H₂O + CoA + NAD⁺ + 2-methyl-3-oxopropanoate

H⁺ + hydrogencarbonate + propanoyl-CoA + NADH

Enzyme

1.2.1.27

PMID

Ortholog

Displaying entries **11 - 20** of 96 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Pongo abelii	100171652	9601_0:0037e2		PONAB08492
Ciona intestinalis	100181655			CIOIN01641
Taeniopygia guttata	100226750			TAEGU24770
Oryctolagus cuniculus	100341559			RABIT09028
Callithrix jacchus	100399116			CALJA01966
Ailuropoda melanoleuca	100470575			AILME17353
Meleagris gallopavo	100541149			MELGA10976
Anolis carolinensis	100555244			ANOCA00180
Nomascus leucogenys	100606200			NOMLE22143
Loxodonta africana	100672226			LOXAF16078

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Last updated: December 9, 2024