Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neurofilament light chain
Summary
- Gene Symbol
-
- NEFL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Cell projection
- Charcot-Marie-Tooth disease
- Coiled coil
- Cytoskeleton
- Direct protein sequencing
- Disease variant
- Glycoprotein
- Intermediate filament
- Methylation
- Neurodegeneration
- Phosphoprotein
- Reference proteome
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P07196 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to toxic substance | ||
| peripheral nervous system axon regeneration | ||
| postsynaptic intermediate filament cytoskeleton organization | ||
| microtubule cytoskeleton organization | ||
| spinal cord development |
GO Hierarchy
- locomotion
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Schaffer collateral - CA1 synapse | ||
| postsynaptic intermediate filament cytoskeleton | ||
| neuromuscular junction | ||
| axon cytoplasm | ||
| axon |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-containing complex binding | ||
| structural constituent of postsynaptic intermediate filament cytoskeleton | ||
| protein-macromolecule adaptor activity | ||
| identical protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Keratin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intermediate filament organization |
| InterPro |
|---|
| Intermediate filament protein, conserved site |
| Intermediate filament, rod domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3213 | demyelinating disease | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050433 | fatal familial insomnia | |
| DOID:0080294 | Charcot-Marie-Tooth disease dominant intermediate G | |
| DOID:0080600 | COVID-19 | |
| DOID:0080832 | mild cognitive impairment | |
| DOID:0110149 | Charcot-Marie-Tooth disease type 1F | |
| DOID:0110165 | Charcot-Marie-Tooth disease type 2E | |
| DOID:10595 | Charcot-Marie-Tooth disease | |
| DOID:10652 | Alzheimer's disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 18039 | MGI:97313 | MOUSE12892 | ||
| 83613 | RGD:621458 | RATNO10439 | ||
| 281348 | BOVIN34763 | |||
| 397822 | Xenbase:XB-GENE-866125 | |||
| 464063 | 9598_0:0025cd | PANTR42193 | ||
| 641444 | MACMU43938 | |||
| 664698 | ZFIN:ZDB-GENE-060312-44 | DANRE42497 | ||
| 793912 | ZFIN:ZDB-GENE-091117-1 | |||
| 100020093 | MONDO04912 | |||
| 100054178 | HORSE26921 |
