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ATPase Na+/K+ transporting subunit alpha 1

Summary

Gene Symbol

ATP1A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

476

PubChem

476

Alliance of Genome Resources

HGNC:799

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Cell membrane
Cell projection
Charcot-Marie-Tooth disease
Direct protein sequencing
Epilepsy
Intellectual disability
Magnesium
Metal-binding
Neurodegeneration
Phosphoprotein
Primary hypomagnesemia
Reference proteome
Sodium/potassium transport
Translocase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P05023	Sodium pump subunit alpha-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
positive regulation of heart contraction	IEA
negative regulation of glucocorticoid biosynthetic process	IEA
positive regulation of striated muscle contraction	IEA
relaxation of cardiac muscle	TAS	23224879
potassium ion import across plasma membrane	IBA IDA ISO ISS	10636900 19542013

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell communication by electrical coupling [inference]

cell communication by electrical coupling involved in cardiac conduction

cell communication involved in cardiac conduction [inference]

cell communication by electrical coupling involved in cardiac conduction

signal transduction [inference]

intracellular signal transduction [inference]

osmosensory signaling pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

relaxation of muscle [inference]

relaxation of cardiac muscle

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

potassium ion homeostasis [inference]

intracellular potassium ion homeostasis

sodium ion homeostasis [inference]

intracellular sodium ion homeostasis

response to stimulus [inference]

response to stress [inference]

response to osmotic stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

response to abiotic stimulus [inference]

response to osmotic stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

response to steroid hormone [inference]

cellular response to steroid hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

response to steroid hormone [inference]

cellular response to steroid hormone stimulus

response to organic cyclic compound [inference]

response to steroid hormone [inference]

cellular response to steroid hormone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus

response to lipid [inference]

response to steroid hormone [inference]

cellular response to steroid hormone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus

response to glycoside

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus

response to oxygen-containing compound [inference]

response to glycoside

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to steroid hormone stimulus

cellular response to lipid [inference]

cellular response to steroid hormone stimulus

cellular response to organic cyclic compound [inference]

cellular response to steroid hormone stimulus

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to osmotic stress [inference]

osmosensory signaling pathway

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

sodium ion transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

proton transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

establishment or maintenance of transmembrane electrochemical gradient

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

sodium ion export across plasma membrane

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction [inference]

positive regulation of striated muscle contraction

positive regulation of blood circulation [inference]

positive regulation of heart contraction

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of multicellular organismal process [inference]

negative regulation of blood circulation [inference]

negative regulation of heart contraction

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

osmosensory signaling pathway

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of striated muscle contraction [inference]

positive regulation of striated muscle contraction

positive regulation of muscle contraction [inference]

positive regulation of striated muscle contraction

regulation of blood circulation [inference]

regulation of heart contraction [inference]

negative regulation of blood circulation [inference]

negative regulation of heart contraction

positive regulation of blood circulation [inference]

positive regulation of heart contraction

positive regulation of multicellular organismal process [inference]

positive regulation of muscle contraction [inference]

positive regulation of striated muscle contraction

positive regulation of blood circulation [inference]

positive regulation of heart contraction

negative regulation of multicellular organismal process [inference]

negative regulation of blood circulation [inference]

negative regulation of heart contraction

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone metabolic process [inference]

regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone metabolic process [inference]

negative regulation of glucocorticoid metabolic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of hormone biosynthetic process [inference]

negative regulation of hormone biosynthetic process [inference]

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of steroid hormone biosynthetic process [inference]

regulation of glucocorticoid biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

negative regulation of steroid hormone biosynthetic process [inference]

negative regulation of glucocorticoid biosynthetic process

regulation of membrane potential [inference]

action potential [inference]

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

membrane repolarization

membrane repolarization during action potential [inference]

membrane repolarization during cardiac muscle cell action potential

cardiac muscle cell membrane repolarization [inference]

membrane repolarization during cardiac muscle cell action potential

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
membrane	ISS
sodium:potassium-exchanging ATPase complex	IBA IDA IGI IPI ISS	10636900 18052210 19542013 35803952
Golgi apparatus	ISS
sarcolemma	IBA ISS
lateral plasma membrane	IDA	11193188

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

sodium:potassium-exchanging ATPase complex

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

transporter complex [inference]

transmembrane transporter complex [inference]

ATPase dependent transmembrane transport complex [inference]

cation-transporting ATPase complex [inference]

sodium:potassium-exchanging ATPase complex

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

organelle membrane

plasma membrane region [inference]

membrane microdomain [inference]

membrane raft

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular vesicle

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

extracellular exosome

postsynaptic specialization [inference]

postsynaptic density

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	11027149 15671290 16730713 17220478 18504258 21228272 21278788 22084111 25012180 30021884 33961781 35271311 35803952
sodium ion binding	ISS
ATP hydrolysis activity	IEA
P-type sodium:potassium-exchanging transporter activity	IBA IDA IGI ISS	10636900 18052210 19542013
protein-folding chaperone binding	IPI	10636900

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

sodium ion transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

binding [inference]

protein binding

transmembrane transporter binding

protein dimerization activity [inference]

protein heterodimerization activity

protein-folding chaperone binding

lipid binding [inference]

steroid binding [inference]

steroid hormone binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

hormone binding [inference]

steroid hormone binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

alkali metal ion binding [inference]

organic cyclic compound binding [inference]

steroid binding [inference]

steroid hormone binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type transmembrane transporter activity [inference]

P-type ion transporter activity [inference]

P-type sodium transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

P-type potassium transmembrane transporter activity [inference]

P-type sodium:potassium-exchanging transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATPase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
P-type calcium transporter activity
calcium ion transmembrane transport
calcium ion transport
intracellular calcium ion homeostasis
monoatomic ion transport
nucleotide binding

Displaying **all 10** entries
InterPro
Cation-transporting P-type ATPase, C-terminal
Cation-transporting P-type ATPase, N-terminal
HAD superfamily
HAD-like superfamily
P-type ATPase, A domain superfamily
P-type ATPase, cytoplasmic domain N
P-type ATPase, haloacid dehalogenase domain
P-type ATPase, phosphorylation site
P-type ATPase, transmembrane domain superfamily
P-type ATPase

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:0060178	familial hemiplegic migraine	Alliance of Genome Resources
DOID:0111558	Charcot-Marie-Tooth disease type 2DD	Alliance of Genome Resources
DOID:10003	sensorineural hearing loss	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:1574	alcohol use disorder	Alliance of Genome Resources
DOID:1826	epilepsy	Alliance of Genome Resources
DOID:863	nervous system disease	Alliance of Genome Resources
DOID:9279	hyperhomocysteinemia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **105** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	11928	MGI:88105	MOUSE37947
Rattus norvegicus	24211	RGD:2167	RATNO24685
Drosophila melanogaster	48971	FB:FBgn0002921
Danio rerio	64612	ZFIN:ZDB-GENE-001212-1	DANRE16588
Danio rerio	64613	ZFIN:ZDB-GENE-001212-2
Danio rerio	64614	ZFIN:ZDB-GENE-001212-3
Danio rerio	64615	ZFIN:ZDB-GENE-001212-4
Danio rerio	64616	ZFIN:ZDB-GENE-001212-5	DANRE44838
Caenorhabditis elegans	179796	WB:WBGene00001137
Danio rerio	245703	ZFIN:ZDB-GENE-020501-1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements