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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NFE2 like bZIP transcription factor 2
Summary
- Gene Symbol
-
- NFE2L2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative splicing
- Coiled coil
- Cytoplasm
- DNA-binding
- Disease variant
- Glycation
- Host-virus interaction
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8V8TN14 |
|
| Q16236 |
|
| A0A8V8TPA8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteasome-mediated ubiquitin-dependent protein catabolic process | ||
| aflatoxin catabolic process | ||
| cellular response to angiotensin | ||
| response to ischemia | ||
| positive regulation of neuron projection development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to stress [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi apparatus | ||
| non-membrane-bounded organelle |
|
|
| plasma membrane | ||
| nucleoplasm | ||
| RNA polymerase II transcription regulator complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| DNA binding | ||
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| transcription coregulator binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- nuclear factor, erythroid 2
- Functional Category
-
- K: Transcription
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| regulation of gene expression |
| regulation of nitrogen compound metabolic process |
| regulation of primary metabolic process |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080547 | metabolic dysfunction-associated steatohepatitis | |
| DOID:0081292 | traumatic brain injury | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:11832 | visual epilepsy | |
| DOID:12858 | Huntington's disease | |
| DOID:13619 | extrahepatic cholestasis | |
| DOID:2841 | asthma | |
| DOID:3021 | acute kidney failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 18024 | MGI:108420 | MOUSE33187 | ||
| 42743 | FB:FBgn0262975 | |||
| 83619 | RGD:620360 | RATNO28860 | ||
| 177343 | WB:WBGene00004804 | |||
| 189139 | WB:WBGene00020961 | |||
| 360149 | ZFIN:ZDB-GENE-030723-2 | DANRE44239 | ||
| 379209 | Xenbase:XB-GENE-17346208 | |||
| 444736 | Xenbase:XB-GENE-943932 | |||
| 478813 | CANLF13999 | |||
| 493217 | Xenbase:XB-GENE-943926 |
