5'-nucleotidase ecto

Summary
Gene Symbol
  • NT5E
Aliases
  • CALJA
  • CD73
  • eN
  • eNT
Organism
Homo sapiens (human)
External Links
NCBI Gene
4907
HGNC
8021
KEGG Gene ID
hsa:4907
PubChem
4907
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • GPI-anchor
  • Hydrolase
  • Metal-binding
  • Nucleotide-binding
  • Reference proteome
  • Signal
  • Transmembrane helix
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
P21589
  • 5'-deoxynucleotidase
  • Ecto-5'-nucleotidase
  • IMP-specific 5'-nucleotidase
  • Thymidylate 5'-phosphatase
Q6NZX3
  • Ecto-5'-nucleotidase
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000135318

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K19970
Name
5'-nucleotidase [EC:3.1.3.5]
References
Disease
Disease Ontology
Displaying entries 1 - 10 of 383 in total
DO ID Disease Name Source
DOID:9088 parapsoriasis
DOID:0050156 idiopathic pulmonary fibrosis
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050589 inflammatory bowel disease
DOID:0050644 arterial calcification of infancy
DOID:0050645 arterial tortuosity syndrome
DOID:0050745 diffuse large B-cell lymphoma
DOID:0050819 obsolete Matthew-Wood syndrome
DOID:0050848 obstructive sleep apnea
DOID:0050854 Muckle-Wells syndrome
The Human Phenotype Ontology
Displaying all 9 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001717 Coronary artery calcification
HP:0003207 Arterial calcification
HP:0004417 Intermittent claudication
HP:0005116 Arterial tortuosity
HP:0005645 Intervertebral disk calcification
HP:0011025 Abnormal cardiovascular system physiology
HP:0011986 Ectopic ossification
HP:0012101 Decreased serum creatinine
Displaying all 2 entries
Disease ID Disease Name
ORPHA:289601
  • hereditary arterial and articular multiple calcification syndrome
OMIM:211800
  • hereditary arterial and articular multiple calcification syndrome

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024