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ATPase plasma membrane Ca2+ transporting 4
Summary
- Gene Symbol
-
- ATP2B4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Calcium transport
- Calmodulin-binding
- Cell membrane
- Direct protein sequencing
- Flagellum
- Magnesium
- Metal-binding
- Phosphoprotein
- Reference proteome
- Translocase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P23634 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of peptidyl-cysteine S-nitrosylation | ||
| negative regulation of calcineurin-NFAT signaling cascade | ||
| positive regulation of protein localization to plasma membrane | ||
| regulation of cardiac conduction | ||
| cellular response to epinephrine stimulus |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| P-type calcium transporter activity | ||
| calmodulin binding | ||
| ATP hydrolysis activity | ||
| calcium ion transmembrane transporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- ATPase
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| monoatomic ion transport |
| nucleotide binding |
| proton export across plasma membrane |
| regulation of intracellular pH |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050429 | Hailey-Hailey disease | |
| DOID:10591 | pre-eclampsia | |
| DOID:11714 | gestational diabetes | |
| DOID:543 | dystonia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 29600 | RGD:621305 | RATNO06921 | ||
| 43787 | FB:FBgn0259214 | |||
| 177004 | WB:WBGene00019875 | |||
| 177089 | WB:WBGene00003153 | |||
| 381290 | MGI:88111 | MOUSE29364 | ||
| 403731 | CANLF14287 | |||
| 446855 | Xenbase:XB-GENE-960661 | |||
| 457646 | 9598_0:000462 | PANTR23418 | ||
| 574317 | MACMU24698 | |||
| 768304 | ZFIN:ZDB-GENE-061027-60 |
