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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sodium voltage-gated channel alpha subunit 3
Summary
- Gene Symbol
-
- Scn3a
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Coiled coil
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Repeat
- Sodium channel
- Transmembrane helix
- Ubl conjugation
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0G2K237 |
|
| P08104 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| behavioral response to pain | ||
| action potential | ||
| response to pyrethroid | ||
| membrane depolarization during action potential | ||
| cellular response to antibiotic |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| neuronal cell body | ||
| voltage-gated sodium channel complex | ||
| plasma membrane | ||
| sarcoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| sodium ion binding |
|
|
| calmodulin binding | ||
| voltage-gated sodium channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- sodium channel protein type 3 subunit alpha
- Functional Category
-
- D: Cell cycle control, cell division, chromosome partitioning
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
| InterPro |
|---|
| Ion transport domain |
| Sodium ion transport-associated domain |
| Voltage-gated Na+ ion channel, cytoplasmic domain |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060170 | generalized epilepsy with febrile seizures plus | |
| DOID:0080420 | developmental and epileptic encephalopathy 62 | |
| DOID:0080422 | Dravet syndrome | |
| DOID:0081424 | familial focal epilepsy with variable foci 4 | |
| DOID:0111294 | generalized epilepsy with febrile seizures plus 2 | |
| DOID:1826 | epilepsy | |
| DOID:2030 | anxiety disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6328 | HGNC:10590 | HUMAN65301 | ||
| 20269 | 10090_1:0006d7 | MGI:98249 | MOUSE31626 | |
| 32619 | FB:FBgn0285944 | |||
| 446050 | TAKRU47949 | |||
| 459699 | PANTR29006 | |||
| 478772 | CANLF13922 | |||
| 534223 | BOVIN24162 | |||
| 559447 | ZFIN:ZDB-GENE-060906-1 | DANRE38971 | ||
| 703178 | MACMU06363 | |||
| 853131 | SGD:S000003449 |
