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NADPH oxidase 4

Summary

Gene Symbol

NOX4

Organism

Homo sapiens (human)

External Links

NCBI Gene

50507

PubChem

50507

Alliance of Genome Resources

HGNC:7891

Annotation

Keyword

Alternative splicing
Cell junction
Cell membrane
Cytoplasm
Disulfide bond
Endoplasmic reticulum
Glycoprotein
NADP
Nucleus
Oxidoreductase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
B7Z529
B3KQ17
Q9NPH5	Kidney oxidase-1 Kidney superoxide-producing NADPH oxidase Renal NAD(P)H-oxidase
B7Z523

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	ISS	10869423
positive regulation of DNA biosynthetic process	IEA
homocysteine metabolic process	IDA	20031578
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA
superoxide anion generation	IBA ISS	10869423

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

reactive oxygen species biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

sulfur compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

reactive oxygen species biosynthetic process

primary metabolic process [inference]

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organonitrogen compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

amino acid metabolic process [inference]

alpha-amino acid metabolic process [inference]

homocysteine metabolic process

sulfur compound metabolic process [inference]

sulfur amino acid metabolic process [inference]

homocysteine metabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

reactive oxygen species metabolic process [inference]

superoxide metabolic process

superoxide anion generation

reactive oxygen species biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

heart process

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

bone resorption

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

bone resorption

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

intracellular chemical homeostasis [inference]

intracellular glucose homeostasis [inference]

cellular response to glucose stimulus

response to stimulus [inference]

response to stress [inference]

defense response

inflammatory response

response to chemical [inference]

response to organic substance [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

response to oxygen-containing compound [inference]

response to carbohydrate [inference]

response to monosaccharide [inference]

response to hexose [inference]

response to glucose [inference]

cellular response to glucose stimulus

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

cellular response to oxygen-containing compound [inference]

cellular response to carbohydrate stimulus [inference]

cellular response to monosaccharide stimulus [inference]

cellular response to hexose stimulus [inference]

cellular response to glucose stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade [inference]

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of DNA biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

regulation of protein tyrosine kinase activity [inference]

positive regulation of protein tyrosine kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein tyrosine kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
membrane	TAS	10869423
focal adhesion	IEA
endoplasmic reticulum membrane	IDA TAS	15927447
perinuclear endoplasmic reticulum	ISS	27525436
NADPH oxidase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

NADPH oxidase complex

catalytic complex [inference]

oxidoreductase complex [inference]

NADPH oxidase complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	15356101 17064675
protein tyrosine kinase binding	ISS	27525436
superoxide-generating NADPH oxidase activity	IEA
superoxide-generating NAD(P)H oxidase activity	IBA IDA	10869423 11032835 15155719 15721269 15927447 16019190 16179589 16230378 16324151 23393389 25062272
oxygen sensor activity	TAS	10869423

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

electron transfer activity

oxidoreductase activity, acting on NAD(P)H [inference]

oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [inference]

NAD(P)H oxidase H2O2-forming activity

NADPH oxidase H202-forming activity

superoxide-generating NAD(P)H oxidase activity

superoxide-generating NADPH oxidase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

modified amino acid binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding

flavin adenine dinucleotide binding

small molecule sensor activity [inference]

oxygen sensor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Respiratory burst

Functional Category

C: Energy production and conversion
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ferric-chelate reductase activity
oxidoreductase activity

Displaying **all 6** entries
InterPro
FAD-binding 8
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Ferric reductase transmembrane component-like domain
Ferric reductase, NAD binding domain
Riboflavin synthase-like beta-barrel

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080547	metabolic dysfunction-associated steatohepatitis	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:9452	steatotic liver disease	Alliance of Genome Resources
DOID:9970	obesity	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	50490		MGI:1354184	MOUSE52339
Rattus norvegicus	85431		RGD:620600	RATNO16136
Bos taurus	378474			BOVIN22802
Pan troglodytes	451709	9598_0:003196
Ciona intestinalis	619226			CIOIN08539
Macaca mulatta	705931			MACMU09316
Pan troglodytes	735636	9598_0:003048		PANTR04028
Monodelphis domestica	100009800			MONDO21852
Ovis aries	100034665			SHEEP10780
Equus caballus	100050321			HORSE39120

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements