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solute carrier family 3 member 2

Summary

Gene Symbol

Slc3a2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

50567

PubChem

50567

Alliance of Genome Resources

RGD:3073

Annotation

Keyword

Amino-acid transport
Cell junction
Cell membrane
Disulfide bond
Glycoprotein
Isopeptide bond
Lysosome
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 4** entries
UniProt	Protein Name
A6HZS2
A0A0H2UHQ0
Q794F9	4F2 cell-surface antigen heavy chain Solute carrier family 3 member 2
A6HZS0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
leucine transport	IDA ISO	10049700 9726963
tyrosine transport	IEA ISO
carbohydrate metabolic process	IEA
L-histidine transport	IDA IEA ISO	10049700
response to muscle activity	IEP	24016666

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to starvation [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

cellular response to stress [inference]

cellular response to starvation [inference]

cellular response to glucose starvation

localization [inference]

establishment of localization [inference]

transport [inference]

hormone transport [inference]

thyroid hormone transport

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

nitrogen compound transport [inference]

amino acid transport [inference]

sulfur amino acid transport [inference]

methionine transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

aromatic amino acid transport [inference]

basic amino acid transport [inference]

histidine transport [inference]

L-histidine transport

branched-chain amino acid transport [inference]

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

valine transport

neutral amino acid transport

isoleucine transport

leucine transport

leucine import across plasma membrane

L-leucine import across plasma membrane

alanine transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-amino acid transport [inference]

L-alanine transport [inference]

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

L-histidine transport

L-alpha-amino acid transmembrane transport [inference]

L-leucine import across plasma membrane

L-alanine transmembrane transport [inference]

L-alanine import across plasma membrane

phenylalanine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

methionine transport

import into cell [inference]

amino acid import across plasma membrane [inference]

leucine import across plasma membrane

L-leucine import across plasma membrane

L-alanine import across plasma membrane

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

thyroid hormone transport

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
amino acid transport complex	IEA ISO
anchoring junction	IEA
melanosome	IEA
basal plasma membrane	IDA	11095508
neuronal cell body	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

amino acid transport complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

plasma membrane region [inference]

cell junction [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

cell body [inference]

neuronal cell body

cell pole [inference]

apical pole of neuron

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
exogenous protein binding	IEA ISO
aromatic amino acid transmembrane transporter activity	IBA IEA ISO
protein homodimerization activity	IEA ISO
double-stranded RNA binding	IEA ISO
neutral L-amino acid secondary active transmembrane transporter activity	IEA ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity

neutral L-amino acid transmembrane transporter activity

alanine transmembrane transporter activity [inference]

L-alanine transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

branched-chain amino acid transmembrane transporter activity [inference]

L-leucine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

neutral L-amino acid secondary active transmembrane transporter activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

exogenous protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

double-stranded RNA binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:0050865	tongue squamous cell carcinoma	Alliance of Genome Resources
DOID:0080202	adenoid cystic carcinoma	Alliance of Genome Resources
DOID:0080899	lung pleomorphic carcinoma	Alliance of Genome Resources
DOID:2671	transitional cell carcinoma	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:5517	stomach carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	175125	WB:WBGene00000225
Drosophila melanogaster	40941	FB:FBgn0037533
Danio rerio	796322	ZFIN:ZDB-GENE-000831-3	DANRE40737
Danio rerio	399488	ZFIN:ZDB-GENE-040122-2
Danio rerio	790938	ZFIN:ZDB-GENE-061215-58
Astyanax mexicanus	103045737		ASTMX05610
Ictalurus punctatus	108267557		ICTPU32872
Electrophorus electricus	113579831		ELEEL24811
Salmo salar	100195278		SALSA37442
Salmo salar	106578137		SALSA90769

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Acknowledgements