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p21 (RAC1) activated kinase 1

Summary

Gene Symbol

PAK1

Organism

Homo sapiens (human)

External Links

NCBI Gene

5058

PubChem

5058

Alliance of Genome Resources

HGNC:8590

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Allosteric enzyme
Alternative splicing
Apoptosis
Cell junction
Cell membrane
Cell projection
Chromosome
Cytoskeleton
Disease variant
Epilepsy
Exocytosis
Intellectual disability
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q13153	Alpha-PAK p21-activated kinase 1 p65-PAK

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 34 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	23333386
Fc-gamma receptor signaling pathway involved in phagocytosis	TAS
branching morphogenesis of an epithelial tube	IMP	20457839
positive regulation of stress fiber assembly	IMP	11864573
wound healing	IMP	12912914

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

protein autophosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation

protein phosphorylation

protein autophosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

protein autophosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

protein autophosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

protein autophosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

protein autophosphorylation

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

intracellular signal transduction

MAPK cascade

cell death [inference]

programmed cell death [inference]

apoptotic process

vesicle-mediated transport [inference]

exocytosis

actin filament-based process [inference]

actin cytoskeleton organization

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation

protein phosphorylation

protein autophosphorylation

cell motility [inference]

cell migration

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoplasmic stress granule

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

export from cell [inference]

secretion by cell [inference]

exocytosis

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

cellular response to stress [inference]

response to starvation [inference]

cellular response to starvation

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to biotic stimulus [inference]

response to lectin [inference]

cellular response to lectin [inference]

stimulatory C-type lectin receptor signaling pathway

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoplasmic stress granule

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cytoplasmic stress granule

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of cell proliferation involved in contact inhibition

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

innate immune response-activating signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-activating cell surface receptor signaling pathway [inference]

innate immune response activating cell surface receptor signaling pathway [inference]

stimulatory C-type lectin receptor signaling pathway

Fc receptor mediated stimulatory signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

Fc receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway [inference]

Fc-gamma receptor signaling pathway involved in phagocytosis

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

intracellular signal transduction

MAPK cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

negative regulation of cell population proliferation [inference]

negative regulation of cell proliferation involved in contact inhibition

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular steroid hormone receptor signaling pathway [inference]

positive regulation of intracellular estrogen receptor signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of cellular component biogenesis [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of cell proliferation involved in contact inhibition

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of protein-containing complex assembly [inference]

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of protein polymerization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of microtubule polymerization or depolymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

positive regulation of protein-containing complex assembly [inference]

positive regulation of protein polymerization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of supramolecular fiber organization [inference]

regulation of microtubule polymerization [inference]

regulation of microtubule nucleation [inference]

positive regulation of microtubule nucleation

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of stress fiber assembly [inference]

positive regulation of stress fiber assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of microtubule polymerization

positive regulation of microtubule nucleation

positive regulation of actin filament bundle assembly [inference]

positive regulation of stress fiber assembly

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of protein serine/threonine kinase activity [inference]

regulation of MAP kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

regulation of JUN kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity [inference]

positive regulation of MAP kinase activity [inference]

positive regulation of JUN kinase activity

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
nuclear membrane	ISS
focal adhesion	IEA
protein-containing complex	IDA	11864573 11950598
ruffle membrane	IEA
plasma membrane	IDA TAS	16278681

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

nuclear membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

Z disc

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell-cell contact zone [inference]

intercalated disc

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10026169 10559936 11030651 11864573 12606577 12624090 12879077 14521508 15350535 16101281 16278681 16407834 16413544 16492808 16628223 17245428 17389360 18325335 18716323 18854161 19270716 19435845 19596003 19693014 19732720 19893577 20810653 20936779 21029865 21167153 21454543 21900206 21988832 22117219 22581261 23175184 23455922 24172987 24625804 24792722 25150978 25416956 25766321 25843002 25852190 26175416 26940976 27012601 29734338 29997244 31515488 31980649 32296183 32814053 33189893 33961781 35271311
protein serine kinase activity	IEA
small GTPase binding	IPI	11950598
protein serine/threonine kinase activity	EXP IBA IDA TAS	10559936 11278486 16278681 17060906 17420447 19667065 20417602 23260667
identical protein binding	IPI	17389360 22153498

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

gamma-tubulin binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

collagen binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein kinase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
nucleotide binding
regulation of MAPK cascade
regulation of axonogenesis

Displaying **all 3** entries
InterPro
Protein kinase domain
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 8** entries
DO ID	Disease Name	Source
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:2154	nephroblastoma	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources
DOID:2671	transitional cell carcinoma	Alliance of Genome Resources
DOID:4001	ovarian carcinoma	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:5419	schizophrenia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	18479		MGI:1339975	MOUSE54162
Rattus norvegicus	29431		RGD:3250	RATNO16290
Drosophila melanogaster	41995		FB:FBgn0044826
Danio rerio	373103		ZFIN:ZDB-GENE-030826-29	DANRE14760
Xenopus laevis	398126		Xenbase:XB-GENE-967720
Xenopus laevis	398782		Xenbase:XB-GENE-17335559
Pan troglodytes	451439	9598_0:0031f2		PANTR03901
Bos taurus	533729			BOVIN22888
Canis lupus familiaris	607885			CANLF08240
Macaca mulatta	698585			MACMU11335

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements