poly(A)-specific ribonuclease

Summary
Gene Symbol
  • PARN
Organism
Homo sapiens (human)
NCBI Gene
5073
PubChem
5073
Alliance of Genome Resources
JoGo
PARN
TogoVar
PARN
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Dyskeratosis congenita
  • Exonuclease
  • Magnesium
  • Metal-binding
  • Nonsense-mediated mRNA decay
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • RNA-binding
  • Reference proteome
Proteins
Displaying all 5 entries
UniProt Protein Name
A0A494C1K5
  • Polyadenylate-specific ribonuclease
A0A494C0Q2
  • Polyadenylate-specific ribonuclease
O95453
  • Deadenylating nuclease
  • Deadenylation nuclease
  • Polyadenylate-specific ribonuclease
B3KN69
  • Polyadenylate-specific ribonuclease
A0A494C1N1
  • Polyadenylate-specific ribonuclease
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
poly(A)-specific ribonuclease
Functional Category
  • L: Replication, recombination and repair
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0070024 autosomal recessive dyskeratosis congenita 6

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026