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ephrin A1

Summary

Gene Symbol

EFNA1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 507319
KEGG Gene ID: bta:507319
PubChem: 507319

Annotation

Keyword

Angiogenesis
Cell membrane
Disulfide bond
GPI-anchor
Reference proteome
Secreted
Signal
Tumor suppressor

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3ZC64

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
ephrin receptor signaling pathway	IEA	22301074 30032202
regulation of peptidyl-tyrosine phosphorylation
axon guidance	IEA	30032202
negative regulation of dendritic spine morphogenesis
angiogenesis

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

regulation of nitrogen compound metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendritic spine morphogenesis

negative regulation of developmental process [inference]

negative regulation of dendritic spine development [inference]

negative regulation of dendritic spine morphogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendritic spine morphogenesis [inference]

negative regulation of dendritic spine morphogenesis

negative regulation of developmental process [inference]

negative regulation of dendritic spine development [inference]

negative regulation of dendritic spine morphogenesis

regulation of dendritic spine development [inference]

negative regulation of dendritic spine development [inference]

negative regulation of dendritic spine morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

regulation of peptidyl-tyrosine phosphorylation

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendritic spine morphogenesis

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendritic spine morphogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendritic spine morphogenesis

regulation of dendritic spine morphogenesis [inference]

negative regulation of dendritic spine morphogenesis

regulation of synapse organization [inference]

regulation of postsynapse organization [inference]

regulation of dendritic spine morphogenesis [inference]

negative regulation of dendritic spine morphogenesis

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of dendritic spine morphogenesis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
side of membrane
extracellular region

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane

side of membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
ephrin receptor binding	IEA	22301074 30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

ephrin receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ephrin

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ephrin receptor binding
ephrin receptor signaling pathway

Displaying **all 5** entries
InterPro
Cupredoxin
Ephrin receptor-binding domain
Ephrin, conserved site
Ephrin-A ectodomain
Ephrin

KEGG BRITE Database

Orthology

K05462

Name

ephrin-A

References

Ortholog

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	1942		HUMAN52472
Mus musculus	13636		MOUSE38698
Rattus norvegicus	94268		RATNO23887
Canis lupus familiaris	490431		CANLF17440
Macaca mulatta	717399		MACMU23048
Pan troglodytes	740136		PANTR22455
Monodelphis domestica	100016521		MONDO12046
Ornithorhynchus anatinus	100085755		ORNAN32197
Sus scrofa	100144501	9823_0:001456
Taeniopygia guttata	100221883		TAEGU14632