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ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

Summary

Gene Symbol

ASAP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

50807

PubChem

50807

Alliance of Genome Resources

HGNC:2720

JoGo

ASAP1

TogoVar

ASAP1

Annotation

Keyword

3D-structure
ANK repeat
Alternative splicing
Cilium biogenesis/degradation
Cytoplasm
GTPase activation
Golgi apparatus
Membrane
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
SH3 domain
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0A0MRE5
Q9ULH1	130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein ADP-ribosylation factor-directed GTPase-activating protein 1 Development and differentiation-enhancing factor 1 PIP2-dependent ARF1 GAP

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
Golgi to plasma membrane protein transport	IC	25673879
positive regulation of GTPase activity
positive regulation of cilium assembly	IC	25673879
cilium assembly	IMP	20393563
cilium assembly	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

establishment of protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

establishment of protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

post-Golgi vesicle-mediated transport [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

organic substance transport [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

nitrogen compound transport [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

Golgi to plasma membrane transport [inference]

Golgi to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium

establishment of protein localization [inference]

protein transport [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

Golgi to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of membrane tubulation

negative regulation of biological process [inference]

negative regulation of developmental process [inference]

negative regulation of dendritic spine development

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of dendritic spine development

regulation of dendritic spine development [inference]

negative regulation of dendritic spine development

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly [inference]

positive regulation of cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of membrane tubulation

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

regulation of cilium assembly [inference]

positive regulation of cilium assembly

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly [inference]

positive regulation of cilium assembly

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

regulation of synapse organization [inference]

regulation of postsynapse organization

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cilium assembly

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of cilium assembly

positive regulation of membrane tubulation

regulation of plasma membrane organization [inference]

regulation of membrane tubulation [inference]

positive regulation of membrane tubulation

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

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GO Term	Evidence Code	PMID
Golgi membrane	IDA	25673879
podosome	IBA
Golgi apparatus	IDA
cytosol	TAS
plasma membrane	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

trans-Golgi network membrane

bounding membrane of organelle [inference]

Golgi membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

centriolar satellite

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

podosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular non-membrane-bounded organelle [inference]

podosome

postsynapse [inference]

dendritic spine

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
phosphatidylserine binding	IEA
GTPase activator activity	IBA
protein binding	IPI	12029088 15090612 16636290 17255943 17474147 18786926 19380743 20936779 21706016 21988832 25673879 28514442 31980649 33961781
phosphatidylinositol-4,5-bisphosphate binding	IEA
phosphatidylinositol-3,4,5-trisphosphate binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylserine binding

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol-3,4,5-trisphosphate binding

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

modified amino acid binding [inference]

phosphatidylserine binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
metal ion binding

Displaying entries **1 - 10** of 13 in total

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InterPro
AH/BAR domain superfamily
ARFGAP/RecO-like zinc finger
ASAP, PH domain
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
Arf GTPase activating protein
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
ArfGAP domain superfamily
BAR domain
PH-like domain superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements