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sorbitol dehydrogenase

Summary

Gene Symbol

SORD

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 508954
KEGG Gene ID: bta:508954
PubChem: 508954

Annotation

Keyword

Flagellum
Membrane
Metal-binding
Mitochondrion
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q58D31	L-iditol 2-dehydrogenase Polyol dehydrogenase Xylitol dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
sorbitol catabolic process	IEA	30032202
flagellated sperm motility

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

Displaying **all 2** entries
GO Term	Evidence Code	PMID
mitochondrial membrane
motile cilium

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

mitochondrial membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium [inference]

motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium [inference]

motile cilium

Displaying **all 3** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA	22301074
D-xylulose reductase activity
L-iditol 2-dehydrogenase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

hexitol dehydrogenase activity [inference]

D-xylulose reductase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alcohol dehydrogenase i

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
metal ion binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
zinc ion binding

Displaying **all 6** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily
Polyketide synthase, enoylreductase domain

KEGG BRITE Database

Orthology

K00008

Name

L-iditol 2-dehydrogenase [EC:1.1.1.14]

References

Rhea

xylitol + NAD⁺

H⁺ + D-xylulose + NADH

Enzyme

1.1.1.9

PMID

17216457

L-iditol + NAD⁺

keto-L-sorbose + H⁺ + NADH

Enzyme

1.1.1.14

PMID

H⁺ + keto-D-fructose + NADH

D-sorbitol + NAD⁺

Enzyme

1.1.1.14

PMID

Ortholog

Displaying entries **11 - 20** of 97 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Sus scrofa	100158181	9823_0:000517		PIGXX14427
Pongo abelii	100173784			PONAB08901
Ciona intestinalis	100184593			CIOIN04253
Salmo salar	100196489			SALSA95658
Taeniopygia guttata	100226453			TAEGU02067
Oryctolagus cuniculus	100355885			RABIT06102
Callithrix jacchus	100405393			CALJA00212
Ailuropoda melanoleuca	100469986			AILME18804
Ictalurus punctatus	100528674			ICTPU22120
Nomascus leucogenys	100594471			NOMLE33155

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024