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proliferating cell nuclear antigen

Summary

Gene Symbol

PCNA

Organism

Homo sapiens (human)

External Links

NCBI Gene

5111

PubChem

5111

Alliance of Genome Resources

HGNC:8729

Annotation

Keyword

3D-structure
Acetylation
DNA repair
DNA replication
DNA-binding
Deafness
Direct protein sequencing
Disease variant
Dwarfism
Host-virus interaction
Isopeptide bond
Methylation
Neurodegeneration
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P12004	Cyclin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
replication fork processing	ISS	24115439
response to L-glutamate	IEA
mitotic telomere maintenance via semi-conservative replication	ISS	24115439
translesion synthesis	IBA IDA	20129063
estrous cycle	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular process [inference]

cell cycle process [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

mitotic cell cycle process [inference]

mitotic telomere maintenance via semi-conservative replication

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

base-excision repair, gap-filling

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication [inference]

leading strand elongation

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

DNA synthesis involved in DNA repair [inference]

translesion synthesis

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

telomere organization [inference]

telomere maintenance [inference]

telomere maintenance via semi-conservative replication [inference]

mitotic telomere maintenance via semi-conservative replication

reproductive process [inference]

multicellular organismal reproductive process [inference]

ovulation cycle [inference]

estrous cycle

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration [inference]

liver regeneration

animal organ development [inference]

heart development

animal organ regeneration [inference]

liver regeneration

gland development [inference]

liver development [inference]

liver regeneration

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

rhythmic process [inference]

ovulation cycle [inference]

estrous cycle

response to stimulus [inference]

response to stress [inference]

response to oxidative stress [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to dexamethasone

response to chemical [inference]

response to acid chemical [inference]

response to amino acid [inference]

response to L-glutamate

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to dexamethasone

response to organonitrogen compound [inference]

response to amino acid [inference]

response to L-glutamate

response to organic cyclic compound [inference]

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to dexamethasone

response to lipid [inference]

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to dexamethasone

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to ketone [inference]

response to dexamethasone

response to inorganic substance [inference]

response to metal ion [inference]

response to cadmium ion

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to amino acid [inference]

response to L-glutamate

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to hydrogen peroxide [inference]

cellular response to hydrogen peroxide

response to estradiol

response to amino acid [inference]

response to L-glutamate

response to ketone [inference]

response to dexamethasone

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

response to salt [inference]

response to L-glutamate

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

mismatch repair

postreplication repair [inference]

translesion synthesis

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to chemical stimulus [inference]

cellular response to chemical stress [inference]

cellular response to oxidative stress [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to reactive oxygen species [inference]

cellular response to hydrogen peroxide

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of nuclease activity [inference]

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of response to stimulus [inference]

positive regulation of DNA repair

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of DNA repair

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of DNA biosynthetic process [inference]

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of DNA metabolic process [inference]

positive regulation of DNA biosynthetic process [inference]

positive regulation of DNA-directed DNA polymerase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of transferase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of transferase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of hydrolase activity [inference]

regulation of nuclease activity [inference]

regulation of deoxyribonuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

positive regulation of hydrolase activity [inference]

positive regulation of nuclease activity [inference]

positive regulation of deoxyribonuclease activity

regulation of transferase activity [inference]

positive regulation of transferase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

regulation of DNA-directed DNA polymerase activity [inference]

positive regulation of DNA-directed DNA polymerase activity

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
nuclear lamina	IEA
PCNA complex	IBA IDA IPI	15681588 24939902
male germ cell nucleus	IEA
chromosome, telomeric region	HDA	19135898
cyclin-dependent protein kinase holoenzyme complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

nuclear protein-containing complex [inference]

enzyme activator complex [inference]

DNA polymerase processivity factor complex [inference]

PCNA complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

cyclin-dependent protein kinase holoenzyme complex

cellular anatomical entity [inference]

replication fork

nuclear replication fork

microtubule organizing center [inference]

centrosome

nuclear body

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

germ cell nucleus [inference]

male germ cell nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10873631 11005803 11022036 11595739 14657243 15225546 15358233 15543136 15550930 15576034 15805117 16000169 16189514 16482215 16510448 16826239 17955473 18316726 18499658 18692475 18719106 19150984 19419956 19505873 19730436 19736315 20457750 20605778 20733054 20849852 21549307 21628590 21856198 21988832 21994455 22021614 22153967 22634751 22681887 22704558 22705370 22759634 22894931 22902628 23000965 23042605 23042607 23527218 24267889 24561620 24695737 25416956 25502805 26030842 26408825 26496610 26711499 26751069 26760506 27107012 27462463 27906959 28191891 28514442 28777577 29290612 29892012 29997244 30554877 30833792 31467278 31515488 32296183 32814053 33961781 35271311 35849344 37398436 8861913 9305916
histone acetyltransferase binding	IPI	24939902
protein-containing complex binding	IDA	11595739
enzyme binding	IPI	24115439
chromatin binding	IDA	23277426 24939902

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity [inference]

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA N-glycosylase activity [inference]

mismatch base pair DNA N-glycosylase activity [inference]

purine-specific mismatch base pair DNA N-glycosylase activity

binding [inference]

protein binding

signaling receptor binding [inference]

receptor tyrosine kinase binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear estrogen receptor binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

identical protein binding

protein-containing complex binding

chromatin binding

mismatch repair complex binding [inference]

MutLalpha complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

damaged DNA binding

double-stranded DNA binding [inference]

mismatched DNA binding [inference]

DNA insertion or deletion binding [inference]

dinucleotide insertion or deletion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

DNA polymerase processivity factor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

DNA polymerase processivity factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PROLIFERATING CELL NUCLEAR ANTIGEN

Functional Category

L: Replication, recombination and repair
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
DNA polymerase processivity factor activity
leading strand elongation
regulation of DNA replication
translesion synthesis

Displaying **all 5** entries
InterPro
DNA clamp superfamily
Proliferating cell nuclear antigen, PCNA, C-terminal
Proliferating cell nuclear antigen, PCNA, N-terminal
Proliferating cell nuclear antigen, PCNA, conserved site
Proliferating cell nuclear antigen, PCNA

Disease

Disease Ontology

Displaying entries **1 - 10** of 17 in total

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DO ID	Disease Name	Source
DOID:0080178	mucositis	Alliance of Genome Resources
DOID:0081385	ataxia-telangiectasia-like disorder-2	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:11446	sciatic neuropathy	Alliance of Genome Resources
DOID:11476	osteoporosis	Alliance of Genome Resources
DOID:12217	Lewy body dementia	Alliance of Genome Resources
DOID:127	leiomyoma	Alliance of Genome Resources
DOID:13603	obstructive jaundice	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources
DOID:2154	nephroblastoma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	18538		MGI:97503	MOUSE34894
Rattus norvegicus	25737		RGD:3269	RATNO26363
Danio rerio	30678		ZFIN:ZDB-GENE-000210-8	DANRE01269
Drosophila melanogaster	35257		FB:FBgn0032813
Drosophila melanogaster	37290		FB:FBgn0005655
Caenorhabditis elegans	177161		WB:WBGene00003955
Xenopus laevis	394328		Xenbase:XB-GENE-972527
Xenopus laevis	398425		Xenbase:XB-GENE-17342178
Ovis aries	443155			SHEEP04353
Pan troglodytes	458081	9598_0:005210		PANTR24311

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements