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lysine methyltransferase 5B

Summary

Gene Symbol

KMT5B

Organism

Homo sapiens (human)

External Links

NCBI Gene

51111

PubChem

51111

Alliance of Genome Resources

HGNC:24283

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Chromosome
Disease variant
Intellectual disability
Isopeptide bond
Metal-binding
Methyltransferase
Myogenesis
Nucleus
Proteomics identification
Reference proteome
Repressor
S-adenosyl-L-methionine
Transcription regulation
Ubl conjugation
Zinc

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A8V8TQB9	[histone H4]-lysine20 N-methyltransferase KMT5B
B7WNX0	[histone H4]-lysine20 N-methyltransferase KMT5B
B7Z5N2	[histone H4]-lysine20 N-methyltransferase KMT5B
Q4FZB7	Lysine N-methyltransferase 5B Lysine-specific methyltransferase 5B Suppressor of variegation 4-20 homolog 1 [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B [histone H4]-lysine20 N-methyltransferase KMT5B
C9J6S5	[histone H4]-lysine20 N-methyltransferase KMT5B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA repair	IMP	28114273
chromatin remodeling	IEA
muscle organ development	IEA
methylation	IEA
positive regulation of isotype switching	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of developmental process [inference]

positive regulation of isotype switching

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of immunoglobulin mediated immune response [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of B cell mediated immunity [inference]

positive regulation of immunoglobulin mediated immune response [inference]

positive regulation of isotype switching

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of isotype switching

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of production of molecular mediator of immune response [inference]

regulation of immunoglobulin production [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of immunoglobulin production [inference]

positive regulation of isotype switching

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA recombination [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

positive regulation of DNA repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair [inference]

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of double-strand break repair via nonhomologous end joining [inference]

positive regulation of double-strand break repair via nonhomologous end joining

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

regulation of lymphocyte activation [inference]

regulation of B cell activation [inference]

regulation of isotype switching [inference]

positive regulation of isotype switching

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of B cell activation [inference]

positive regulation of isotype switching

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GO Term	Evidence Code	PMID
condensed chromosome, centromeric region	IEA
fibrillar center	IDA
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

cytoskeleton [inference]

microtubule cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

cytoskeleton [inference]

microtubule cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intercellular bridge

chromosomal region [inference]

chromosome, centromeric region [inference]

condensed chromosome, centromeric region

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
chromatin binding	IDA	28114273
protein binding	IPI	19074285 32296183
histone methyltransferase activity	IDA	17707234
histone H4K20 methyltransferase activity	IDA	24396869
histone H4K20 methyltransferase activity	IMP	28114273

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H4K20 methyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H4K20 methyltransferase activity

histone methyltransferase activity

histone H4 methyltransferase activity

histone H4K20 methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H4K20 methyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H4K20 methyltransferase activity

histone methyltransferase activity

histone H4 methyltransferase activity

histone H4K20 methyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity

histone H4 methyltransferase activity

histone H4K20 methyltransferase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

protein-containing complex binding [inference]

chromatin binding

sulfur compound binding [inference]

S-adenosyl-L-methionine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

histone-lysine n-methyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
histone H4K20 methyltransferase activity
methylation
transferase activity

Displaying **all 4** entries
InterPro
Histone-lysine N-methyltransferase Suv4-20/Set9
Histone-lysine N-methyltransferase, N-terminal domain
SET domain superfamily
SET domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080232	autosomal dominant intellectual developmental disorder 51	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	51111	Xenbase:XB-GENE-852757
Drosophila melanogaster	84787	FB:FBgn0025639
Mus musculus	225888		MOUSE25544
Rattus norvegicus	361688		RATNO16726
Pan troglodytes	451378		PANTR03614
Canis lupus familiaris	483690		CANLF05961
Danio rerio	572849		DANRE13545
Macaca mulatta	710481		MACMU09813
Monodelphis domestica	100010281		MONDO00086
Equus caballus	100053438		HORSE05723

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements