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pericentrin

Summary

Gene Symbol

PCNT

Organism

Homo sapiens (human)

External Links

NCBI Gene

5116

PubChem

5116

Alliance of Genome Resources

HGNC:16068

Annotation

Keyword

Alternative splicing
Calmodulin-binding
Coiled coil
Cytoskeleton
Dwarfism
Microtubule
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
O95613	Kendrin Pericentrin-B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of intracellular protein transport	IMP	22797915
microtubule cytoskeleton organization	IMP	18955030
microtubule nucleation	IBA
mitotic spindle organization	IBA IMP	25220058
cilium assembly	IDA	15337773

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

microtubule nucleation

spindle organization [inference]

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

signal transduction

cell cycle process [inference]

spindle organization [inference]

mitotic spindle organization

mitotic cell cycle process [inference]

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

microtubule nucleation

spindle organization [inference]

mitotic spindle organization

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of cellular process [inference]

signal transduction

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
microtubule	IEA
membrane	HDA	19946888
centriolar satellite	IDA	22797915
centriole	IDA	24421332
centrosome	IDA	18955030 19543530 20186884 21399614 22797915 27137183

GO Hierarchy

cellular component

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

centriole

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	12812986 15094396 16980960 18955030 20466722 22797915 24816561 25503564 26496610 26638075
calmodulin binding	IEA
molecular adaptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

calmodulin binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

A-kinase anchoring protein 9

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
A-kinase anchor protein 9/Pericentrin
Pericentrin/AKAP-450 centrosomal targeting domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060609	microcephalic osteodysplastic primordial dwarfism type II	Alliance of Genome Resources
DOID:14250	Down syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 33 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	18541		MGI:102722	MOUSE02371
Rattus norvegicus	309692		RGD:1595865	RATNO22725
Danio rerio	325536		ZFIN:ZDB-GENE-030829-26
Pan troglodytes	474062	9598_0:0052ab		PANTR25869
Bos taurus	510855			BOVIN15541
Drosophila melanogaster	3772382		FB:FBgn0086690
Oryctolagus cuniculus	100359065			RABIT05012
Pongo abelii	100437499	9601_0:004ef1		PONAB21496
Nomascus leucogenys	100603386			NOMLE23796
Cavia porcellus	100731251			CAVPO22531