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toll like receptor 7

Summary

Gene Symbol

TLR7

Organism

Homo sapiens (human)

External Links

NCBI Gene

51284

PubChem

51284

Alliance of Genome Resources

HGNC:15631

Annotation

Keyword

3D-structure
Cytoplasmic vesicle
Disease variant
Endoplasmic reticulum
Endosome
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Lysosome
Receptor
Reference proteome
Repeat
Signal
Systemic lupus erythematosus
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9NYK1
B2R9N9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
toll-like receptor signaling pathway	IBA
inflammatory response	IEA
canonical NF-kappaB signal transduction	IMP	35477763
canonical NF-kappaB signal transduction	IBA
I-kappaB phosphorylation	IDA	19740627

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response [inference]

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

canonical NF-kappaB signal transduction

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

I-kappaB phosphorylation

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

immune response [inference]

innate immune response

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to other organism [inference]

innate immune response

defense response to symbiont [inference]

defense response to virus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cGMP

response to organic cyclic compound [inference]

response to purine-containing compound [inference]

response to cGMP

response to organophosphorus [inference]

response to cGMP

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cGMP

response to oxygen-containing compound [inference]

response to cGMP

cellular response to stimulus [inference]

cellular response to stress [inference]

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

positive regulation of inflammatory response

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway [inference]

pattern recognition receptor signaling pathway [inference]

toll-like receptor signaling pathway

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular receptor signaling pathway [inference]

cytoplasmic pattern recognition receptor signaling pathway [inference]

endolysosomal toll-like receptor signaling pathway [inference]

intracellular signal transduction [inference]

MAPK cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

canonical NF-kappaB signal transduction

stress-activated protein kinase signaling cascade [inference]

stress-activated MAPK cascade [inference]

JNK cascade

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of non-canonical NF-kappaB signal transduction [inference]

positive regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

positive regulation of macrophage cytokine production

regulation of type I interferon production [inference]

positive regulation of type I interferon production [inference]

regulation of interferon-alpha production [inference]

positive regulation of interferon-alpha production

regulation of interferon-beta production [inference]

positive regulation of interferon-beta production

regulation of chemokine production [inference]

positive regulation of chemokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of interleukin-6 production [inference]

positive regulation of interleukin-6 production

regulation of interleukin-8 production [inference]

positive regulation of interleukin-8 production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of macrophage cytokine production

positive regulation of type I interferon production [inference]

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
cytoplasm	IDA	19740627
lysosome	ISS
endosome	ISS
endoplasmic reticulum	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

endolysosome membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

endolysosome membrane

endosome membrane

endolysosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

endocytic vesicle [inference]

phagocytic vesicle [inference]

early phagosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
double-stranded RNA binding	IDA	16111635
single-stranded RNA binding	ISS
single-stranded RNA binding	IMP	35477763
protein binding	IPI	33432245
siRNA binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

regulatory RNA binding [inference]

siRNA binding

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

twinfilin

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
actin binding
actin filament binding
actin filament depolymerization
actin monomer binding
barbed-end actin filament capping
negative regulation of actin filament polymerization
positive regulation of neuron projection development
regulation of lamellipodium assembly
sequestering of actin monomers

Displaying **all 3** entries
InterPro
ADF-H/Gelsolin-like domain superfamily
Actin-depolymerising factor homology domain
Twinfilin

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080600	COVID-19	Alliance of Genome Resources
DOID:0112063	X-Linked immunodeficiency 74	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **109** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	170744	FB:FBgn0261269
Drosophila melanogaster	174079	FB:FBgn0028888
Drosophila melanogaster	224109	FB:FBgn0261269
Drosophila melanogaster	303875	FB:FBgn0261269
Rattus norvegicus	317468		RATNO45135
Drosophila melanogaster	375387	FB:FBgn0261269
Drosophila melanogaster	434215	FB:FBgn0261269
Drosophila melanogaster	445318	FB:FBgn0261269
Pan troglodytes	473521		PANTR45500
Canis lupus familiaris	491743		CANLF19561

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements