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protocadherin 12

Summary

Gene Symbol

PCDH12

Organism

Homo sapiens (human)

External Links

NCBI Gene

51294

PubChem

51294

Alliance of Genome Resources

HGNC:8657

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Disease variant
Epilepsy
Glycoprotein
Intellectual disability
Phosphoprotein
Primary microcephaly
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NPG4	Vascular cadherin-2 Vascular endothelial cadherin-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycogen metabolic process	IEA
homophilic cell adhesion via plasma membrane adhesion molecules	IEA
neuron recognition	TAS	10380929
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA
labyrinthine layer development	IEA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell recognition [inference]

neuron recognition

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

developmental process [inference]

anatomical structure development [inference]

labyrinthine layer development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cell-cell junction	IEA
plasma membrane	IBA
extracellular exosome	HDA	23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying 1 entry
GO Term	Evidence Code	PMID
calcium ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **31 - 40** of 98 in total

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Species	Gene ID	Orthologous MAtrix
Pan paniscus	100975512	PANPA32794
Pan troglodytes	471677	PANTR36426
Pongo abelii	100438246	PONAB29917
Canis lupus familiaris	487191	CANLF06664
Vulpes vulpes	112934686	VULVU03174
Ursus americanus	123790214	URSAM12078
Ailuropoda melanoleuca	100464877	AILME19461
Mustela putorius furo	101693619	MUSPF16686
Felis catus	101081023	FELCA00188
Panthera leo	122219566	PANLE12222