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potassium two pore domain channel subfamily K member 9

Summary

Gene Symbol

KCNK9

Organism

Homo sapiens (human)

External Links

NCBI Gene

51305

PubChem

51305

Alliance of Genome Resources

HGNC:6283

JoGo

KCNK9

TogoVar

KCNK9

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Glycoprotein
Intellectual disability
Metal-binding
Mitochondrion inner membrane
Potassium channel
Proteomics identification
Reference proteome
Sodium channel
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NPC2	Acid-sensitive potassium channel protein TASK-3 TWIK-related acid-sensitive K(+) channel 3 Two pore potassium channel KT3.2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
potassium ion transport	NAS	11042359
visual perception	ISS
stabilization of membrane potential
sodium ion transmembrane transport	IEA
regulation of resting membrane potential	ISS

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

response to stimulus [inference]

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of endocrine process [inference]

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of action potential [inference]

regulation of action potential firing rate

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of membrane potential [inference]

regulation of action potential [inference]

regulation of action potential firing rate

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrial inner membrane	ISS
plasma membrane	TAS
plasma membrane	IDA	11042359 23169818
plasma membrane	IBA
synaptic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
potassium channel activity	IDA	11042359
sodium channel activity	IDA	22948150
protein binding	IPI	23169818
outward rectifier potassium channel activity	IDA	26919430 38630723
outward rectifier potassium channel activity	IBA