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potassium two pore domain channel subfamily K member 9

Summary

Gene Symbol

KCNK9

Organism

Homo sapiens (human)

External Links

NCBI Gene

51305

PubChem

51305

Alliance of Genome Resources

HGNC:6283

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Glycoprotein
Intellectual disability
Potassium channel
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NPC2	Acid-sensitive potassium channel protein TASK-3 TWIK-related acid-sensitive K(+) channel 3 Two pore potassium channel KT3.2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
potassium ion import across plasma membrane	IBA IDA	11042359
stabilization of membrane potential
potassium ion transport	NAS	11042359
potassium ion transmembrane transport

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

stabilization of membrane potential

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA IDA TAS	11042359
synaptic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying **all 3** entries
GO Term	Evidence Code	PMID
potassium channel activity	IDA	11042359
outward rectifier potassium channel activity	IBA IDA	26919430
potassium ion leak channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

narrow pore channel activity [inference]

leak channel activity [inference]

potassium ion leak channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Potassium channel

Functional Category

E: Amino acid transport and metabolism
K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
outward rectifier potassium channel activity
potassium channel activity
potassium ion leak channel activity
stabilization of membrane potential

Displaying **all 2** entries
InterPro
Potassium channel domain
Two pore domain potassium channel

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050675	Birk-Barel syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 60 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	41125		FB:FBgn0037690
Drosophila melanogaster	41671		FB:FBgn0038165
Rattus norvegicus	84429		RGD:621451	RATNO39440
Caenorhabditis elegans	173613		WB:WBGene00006318
Mus musculus	223604		MGI:3521816	MOUSE15618
Pan troglodytes	464416	9598_0:0024da		PANTR43329
Xenopus laevis	494803		Xenbase:XB-GENE-6255084
Danio rerio	799704		ZFIN:ZDB-GENE-070705-260
Monodelphis domestica	100027125			MONDO18967
Equus caballus	100058202			HORSE42860