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potassium two pore domain channel subfamily K member 9

Summary

Gene Symbol

KCNK9

Organism

Homo sapiens (human)

External Links

NCBI Gene

51305

PubChem

51305

Alliance of Genome Resources

HGNC:6283

JoGo

KCNK9

TogoVar

KCNK9

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Disease variant
Glycoprotein
Intellectual disability
Metal-binding
Mitochondrion inner membrane
Potassium channel
Proteomics identification
Reference proteome
Sodium channel
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NPC2	Acid-sensitive potassium channel protein TASK-3 TWIK-related acid-sensitive K(+) channel 3 Two pore potassium channel KT3.2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
negative regulation of aldosterone secretion	ISS

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

response to stimulus [inference]

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH [inference]

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of lipid localization [inference]

regulation of lipid transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of transport [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of lipid localization [inference]

negative regulation of lipid transport [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of secretion by cell [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of secretion by cell [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of endocrine process [inference]

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

negative regulation of multicellular organismal process [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of action potential [inference]

regulation of action potential firing rate

regulation of biological quality [inference]

regulation of hormone levels [inference]

regulation of hormone secretion [inference]

negative regulation of hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of steroid hormone secretion [inference]

negative regulation of steroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of corticosteroid hormone secretion [inference]

negative regulation of corticosteroid hormone secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of mineralocorticoid secretion [inference]

negative regulation of mineralocorticoid secretion [inference]

negative regulation of aldosterone secretion

regulation of aldosterone secretion [inference]

negative regulation of aldosterone secretion

regulation of membrane potential [inference]

regulation of action potential [inference]

regulation of action potential firing rate

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrial inner membrane	ISS
plasma membrane	TAS
plasma membrane	IDA	11042359 23169818
plasma membrane	IBA
synaptic vesicle	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
potassium ion leak channel activity	IBA
identical protein binding	IDA	38630723
metal ion binding	IEA
protein heterodimerization activity	IDA	23169818

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

narrow pore channel activity [inference]

leak channel activity [inference]

potassium ion leak channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

outward rectifier potassium channel activity

potassium ion leak channel activity

sodium ion transmembrane transporter activity [inference]

sodium channel activity

binding [inference]

protein binding

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050675	Birk-Barel syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements