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all-trans retinoic acid induced differentiation factor

Summary

Gene Symbol

ATRAID

Organism

Homo sapiens (human)

External Links

NCBI Gene

51374

PubChem

51374

Alliance of Genome Resources

HGNC:24090

Annotation

Keyword

Alternative promoter usage
Alternative splicing
Cell membrane
Differentiation
Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Lysosome
Nucleus
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6UW56	Apoptosis-related protein 3 p18

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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2
GO Term	Evidence Code	PMID
cell differentiation	IEA
negative regulation of osteoblast proliferation	IDA	21723284

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell differentiation

transmembrane transport [inference]

xenobiotic transmembrane transport

developmental process [inference]

cellular developmental process [inference]

cell differentiation

localization [inference]

establishment of localization [inference]

transport [inference]

xenobiotic transport [inference]

xenobiotic transmembrane transport

transmembrane transport [inference]

xenobiotic transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of nitrogen compound metabolic process [inference]

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of osteoblast proliferation [inference]

negative regulation of osteoblast proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cellular process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of osteoblast proliferation

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of ossification [inference]

positive regulation of bone mineralization

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IBA
plasma membrane	IEA
nuclear envelope	IDA	21723284
perinuclear region of cytoplasm	IDA	21723284
lysosomal membrane	IDA	29745899

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	18388313 21723284 29745899 32296183
xenobiotic transmembrane transporter activity	IDA	29745899
molecular_function	ND

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

xenobiotic transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

All-trans retinoic acid-induced differentiation factor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
positive regulation of osteoblast differentiation

Displaying **all 2** entries
InterPro
All-trans retinoic acid-induced differentiation factor
EGF-like domain

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	298841		RGD:1311605
Mus musculus	381629		MGI:1918918
Canis lupus familiaris	475699			CANLF04977
Xenopus tropicalis	496775		Xenbase:XB-GENE-5918653
Danio rerio	553468		ZFIN:ZDB-GENE-040724-177	DANRE19272
Macaca mulatta	699201			MACMU07418
Xenopus laevis	734442		Xenbase:XB-GENE-5918699
Pan troglodytes	740920	9598_0:000ba1		PANTR27259
Monodelphis domestica	100031033			MONDO09409
Equus caballus	100071247			HORSE09735

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: December 9, 2024