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LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

LFNG

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 516209
KEGG Gene ID: bta:516209
PubChem: 516209

Annotation

Keyword

Developmental protein
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2KJ92	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
T cell differentiation
somitogenesis
pattern specification process	IEA	22301074
marginal zone B cell differentiation
negative regulation of Notch signaling pathway involved in somitogenesis

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte differentiation [inference]

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte differentiation [inference]

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

T cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

lymphocyte differentiation [inference]

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell activation involved in immune response [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

pattern specification process

regionalization [inference]

anterior/posterior pattern specification [inference]

somitogenesis

segmentation [inference]

somitogenesis

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

somitogenesis

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation [inference]

mature B cell differentiation [inference]

mature B cell differentiation involved in immune response [inference]

marginal zone B cell differentiation

T cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

regulation of Notch signaling pathway involved in somitogenesis [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

regulation of Notch signaling pathway involved in somitogenesis [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

regulation of Notch signaling pathway involved in somitogenesis [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway [inference]

negative regulation of Notch signaling pathway involved in somitogenesis

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding
O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K05948

Name

fringe [EC:2.4.1.222]

References

9187150

Rhea

RHEA:70531

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

RHEA:70511

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.222

PMID

Ortholog

Displaying entries **31 - 40** of 61 in total

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Species	Gene ID	Orthologous MAtrix
Cricetulus griseus	100762397	CRIGR01825
Mus musculus	16848	MOUSE46943
Rattus norvegicus	170905	RATNO05213
Cavia porcellus	100730084	CAVPO13681
Octodon degus	101587790	OCTDE07655
Melopsittacus undulatus	101873005	MELUD13863
Monodelphis domestica	100012518	MONDO28681
Anolis carolinensis	100565009	ANOCA14874
Vombatus ursinus	114052393	VOMUR04414
Microcebus murinus	105868435	MICMU02527