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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ghrelin and obestatin prepropeptide
Summary
- Gene Symbol
-
- GHRL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Amidation
- Direct protein sequencing
- Hormone
- Lipoprotein
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9UBU3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of locomotion | ||
| positive regulation of multicellular organism growth | ||
| negative regulation of tumor necrosis factor production | ||
| positive regulation of sprouting angiogenesis | ||
| positive regulation of MAPK cascade |
GO Hierarchy
- negative regulation of locomotion
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of secretion [inference]
positive regulation of transport [inference]
regulation of protein transport [inference]
regulation of peptide transport [inference]
regulation of cellular localization [inference]
regulation of circadian rhythm [inference]
positive regulation of biological process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of transport [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell population proliferation
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular localization [inference]
regulation of secretion by cell [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of behavior [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum lumen | ||
| glutamatergic synapse | ||
| extracellular region | ||
| axon | ||
| postsynapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| ghrelin receptor binding | ||
| protein tyrosine kinase activator activity | ||
| growth hormone-releasing hormone activity | ||
| protein binding | ||
| G protein-coupled receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050848 | obstructive sleep apnea | |
| DOID:11981 | morbid obesity | |
| DOID:11983 | Prader-Willi syndrome | |
| DOID:1287 | cardiovascular system disease | |
| DOID:3125 | multiple endocrine neoplasia | |
| DOID:3525 | middle cerebral artery infarction | |
| DOID:4914 | esophagus adenocarcinoma | |
| DOID:783 | end stage renal disease | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9743 | diabetic neuropathy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102354515 | LATCH12290 | ||
| 798613 | ZFIN:ZDB-GENE-070622-2 | ||
| 109311132 | CROPO17784 | ||
| 100303671 | MELGA03986 | ||
| 105585781 | CERAT02406 | ||
| 102136682 | MACFA27685 | ||
| 105477694 | MACNE19306 | ||
| 105549536 | MANLE27235 | ||
| 101154276 | GORGO27951 | ||
| 100984734 | PANPA27214 |
