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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
serpin family F member 1
Summary
- Gene Symbol
-
- SERPINF1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Dwarfism
- Glycoprotein
- Osteogenesis imperfecta
- Phosphoprotein
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P36955 |
|
| A0A140VKF3 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to arsenic-containing substance | ||
| positive regulation of neuron projection development | ||
| negative regulation of epithelial cell proliferation involved in prostate gland development | ||
| negative regulation of endopeptidase activity | ||
| response to peptide |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon hillock | ||
| collagen-containing extracellular matrix | ||
| basement membrane | ||
| extracellular region | ||
| melanosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| serine-type endopeptidase inhibitor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor),
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| negative regulation of angiogenesis |
| positive regulation of neurogenesis |
| serine-type endopeptidase inhibitor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080547 | metabolic dysfunction-associated steatohepatitis | |
| DOID:0110350 | osteogenesis imperfecta type 6 | |
| DOID:10584 | retinitis pigmentosa | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1074 | kidney failure | |
| DOID:10762 | portal hypertension | |
| DOID:11168 | anogenital venereal wart | |
| DOID:11382 | corneal neovascularization | |
| DOID:11446 | sciatic neuropathy | |
| DOID:12986 | leukostasis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20317 | MGI:108080 | MOUSE03173 | ||
| 35519 | FB:FBgn0263109 | |||
| 36931 | FB:FBgn0034195 | |||
| 43642 | FB:FBgn0039795 | |||
| 281386 | BOVIN12504 | |||
| 287526 | RGD:631369 | RATNO00887 | ||
| 394686 | Xenbase:XB-GENE-945026 | |||
| 444412 | Xenbase:XB-GENE-945031 | |||
| 447800 | ZFIN:ZDB-GENE-040912-2 | DANRE21467 | ||
| 468137 | 9598_0:00457e | PANTR13198 |
