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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Summary
- Gene Symbol
-
- PFKFB1
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| gluconeogenesis | ||
| negative regulation of glycolytic process through fructose-6-phosphate |
GO Hierarchy
biological process
metabolic process [inference]
nitrogen compound metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
catabolic process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
primary metabolic process [inference]
small molecule metabolic process [inference]
organic substance metabolic process [inference]
organophosphate metabolic process [inference]
organic cyclic compound metabolic process [inference]
organonitrogen compound metabolic process [inference]
organic substance catabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular aromatic compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
aromatic compound catabolic process [inference]
phosphorus metabolic process [inference]
phosphate-containing compound metabolic process [inference]
organophosphate metabolic process [inference]
cellular nitrogen compound metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
cellular nitrogen compound catabolic process [inference]
cellular catabolic process [inference]
heterocycle metabolic process [inference]
nucleobase-containing compound metabolic process [inference]
heterocycle catabolic process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
negative regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
regulation of cellular catabolic process [inference]
regulation of phosphorus metabolic process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| fructose-6-phosphate binding | ||
| kinase binding | ||
| fructose-2,6-bisphosphate 2-phosphatase activity | ||
| ATP binding | ||
| protein binding |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050782 | Zollinger-Ellison syndrome | |
| DOID:10534 | stomach cancer | |
| DOID:162 | cancer | |
| DOID:2018 | hyperinsulinism |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 172147 | WB:WBGene00022456 | ||
| 177363 | WB:WBGene00019295 | ||
| 32938 | FB:FBgn0027621 | ||
| 102352785 | LATCH07933 | ||
| 327453 | ZFIN:ZDB-GENE-030131-5664 | ||
| 100330415 | ZFIN:ZDB-GENE-090312-154 | ||
| 495408 | Xenbase:XB-GENE-957713 | ||
| 108704801 | Xenbase:XB-GENE-17337971 | ||
| 100488795 | Xenbase:XB-GENE-957710 | ||
| 113443245 | PSETE15869 |
