GlyCosmos Portal

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GO Term	Evidence Code	PMID
fructose-6-phosphate binding	IBA IDA	6444721
6-phosphofructokinase activity	IBA IDA IMP	22923583 6227635 6444532 6444721 8780720
kinase binding	IPI	6444721
AMP binding	IBA
monosaccharide binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

identical protein binding

carbohydrate binding [inference]

monosaccharide binding

fructose binding

small molecule binding [inference]

monosaccharide binding

fructose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

AMP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

fructose-6-phosphate binding

cation binding [inference]

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

fructose-6-phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00850

Name

6-phosphofructokinase 1 [EC:2.7.1.11]

References

Rhea

RHEA:16109

ATP + β-D-fructose 6-phosphate

H⁺ + β-D-fructose 1,6-bisphosphate + ADP

Enzyme

2.7.1.11

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of 28 in total

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DO ID	Disease Name	Source
DOID:0014667	disease of metabolism	Alliance of Genome Resources
DOID:0060162	dentatorubral-pallidoluysian atrophy	DisGeNET
DOID:0080220	obsolete major affective disorder 1	DisGeNET
DOID:0080221	obsolete major affective disorder 2	DisGeNET
DOID:0111040	glycogen storage disease IXd	DisGeNET
DOID:0111041	glycogen storage disease IXb	DisGeNET
DOID:0111042	glycogen storage disease IXa	DisGeNET
DOID:0111043	glycogen storage disease IXc	DisGeNET
DOID:0111452	progressive myoclonus epilepsy 1A	DisGeNET
DOID:14250	Down syndrome	DisGeNET

Ortholog

Displaying entries **41 - 50** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Panthera leo	122198570		PANLE07958
Balaenoptera musculus	118894644		BALMU18744
Equus caballus	100056927		HORSE24829
Sus scrofa	100621757		PIGXX06247
Bos taurus	508683		BOVIN15483
Ovis aries	443164		SHEEP01905
Dipodomys ordii	105993995		DIPOR19675
Cricetulus griseus	100762127		CRIGR07624
Mus musculus	18641	MGI:97547	MOUSE02474
Rattus norvegicus	25741	RGD:3311	RATNO22458

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements