GlyCosmos Portal

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GO Term	Evidence Code	PMID
fructose binding	IDA	8780720
metal ion binding	IEA
ATP binding	IBA IDA	8780720
protein binding	IPI	21988832 22923583 25416956 6444721
identical protein binding	IBA IPI	25416956 6444721

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

identical protein binding

carbohydrate binding [inference]

monosaccharide binding

fructose binding

small molecule binding [inference]

monosaccharide binding

fructose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

AMP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

fructose-6-phosphate binding

cation binding [inference]

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

fructose-6-phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00850

Name

6-phosphofructokinase 1 [EC:2.7.1.11]

References

Rhea

RHEA:16109

ATP + β-D-fructose 6-phosphate

H⁺ + β-D-fructose 1,6-bisphosphate + ADP

Enzyme

2.7.1.11

PMID

Disease

Disease Ontology

Displaying entries **21 - 28** of 28 in total

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DO ID	Disease Name	Source
DOID:3534	Lafora disease	DisGeNET
DOID:3535	Unverricht-Lundborg syndrome	DisGeNET
DOID:3571	liver cancer	DisGeNET
DOID:6419	tetralogy of Fallot	DisGeNET
DOID:684	hepatocellular carcinoma	DisGeNET
DOID:891	progressive myoclonus epilepsy	DisGeNET
DOID:9266	cystinuria	DisGeNET
DOID:9870	galactosemia	DisGeNET

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	179335	WB:WBGene00008230
Caenorhabditis elegans	180583	WB:WBGene00022199
Drosophila melanogaster	36060	FB:FBgn0003071
Callorhinchus milii	103182881		CALMI26011
Danio rerio	550259	ZFIN:ZDB-GENE-050417-62	DANRE03150
Danio rerio	570106	ZFIN:ZDB-GENE-121207-1	DANRE45000
Astyanax mexicanus	103032887		ASTMX14766
Astyanax mexicanus	103036959		ASTMX04880
Ictalurus punctatus	108271376		ICTPU01094
Electrophorus electricus	113577922		ELEEL21036

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements