GlyCosmos Portal

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GO Term	Evidence Code	PMID
fructose-6-phosphate binding	IBA IDA	6444721
6-phosphofructokinase activity	IBA IDA IMP	22923583 6227635 6444532 6444721 8780720
kinase binding	IPI	6444721
AMP binding	IBA
monosaccharide binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

carbohydrate kinase activity [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

phosphofructokinase activity [inference]

6-phosphofructokinase activity

binding [inference]

protein binding

enzyme binding [inference]

kinase binding

identical protein binding

carbohydrate binding [inference]

monosaccharide binding

fructose binding

small molecule binding [inference]

monosaccharide binding

fructose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

AMP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

fructose-6-phosphate binding

cation binding [inference]

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

fructose-6-phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00850

Name

6-phosphofructokinase 1 [EC:2.7.1.11]

References

Rhea

RHEA:16109

ATP + β-D-fructose 6-phosphate

H⁺ + β-D-fructose 1,6-bisphosphate + ADP

Enzyme

2.7.1.11

PMID

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:3534	Lafora disease	DisGeNET
DOID:3535	Unverricht-Lundborg syndrome	DisGeNET
DOID:3571	liver cancer	DisGeNET
DOID:6419	tetralogy of Fallot	DisGeNET
DOID:684	hepatocellular carcinoma	DisGeNET
DOID:891	progressive myoclonus epilepsy	DisGeNET
DOID:9266	cystinuria	DisGeNET
DOID:9870	galactosemia	DisGeNET

Ortholog

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Species	Gene ID	Orthologous MAtrix
Crocodylus porosus	109308666	CROPO14973
Pseudonaja textilis	113436780	PSETE08208
Serinus canaria	103815490	SERCA09207
Sarcophilus harrisii	100929505	SARHA18519
Callithrix jacchus	100393627	CALJA22390
Cercocebus atys	105575518	CERAT16494
Macaca fascicularis	102130836	MACFA28324
Macaca mulatta	722173	MACMU30895
Macaca nemestrina	105472537	MACNE05231
Papio anubis	101025579	PAPAN29441

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements