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ELOVL fatty acid elongase 4

Summary

Gene Symbol

ELOVL4

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 532015
KEGG Gene ID: bta:532015
PubChem: 532015

Annotation

Keyword

Endoplasmic reticulum
Fatty acid biosynthesis
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
A5PKE6	3-keto acyl-CoA synthase ELOVL4 ELOVL fatty acid elongase 4 Very long chain 3-ketoacyl-CoA synthase 4 Very long chain 3-oxoacyl-CoA synthase 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
sphingolipid biosynthetic process	IEA	30032202
fatty acid elongation, monounsaturated fatty acid	IEA	30032202
fatty acid elongation, polyunsaturated fatty acid	IEA	30032202
fatty acid elongation, saturated fatty acid	IEA	22301074 30032202
very long-chain fatty acid biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

very long-chain fatty acid metabolic process [inference]

very long-chain fatty acid biosynthetic process

fatty acid biosynthetic process [inference]

fatty acid elongation [inference]

fatty acid elongation, saturated fatty acid

fatty acid elongation, unsaturated fatty acid [inference]

very long-chain fatty acid biosynthetic process

membrane lipid metabolic process [inference]

sphingolipid metabolic process [inference]

sphingolipid biosynthetic process

membrane lipid biosynthetic process [inference]

sphingolipid biosynthetic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202
endoplasmic reticulum	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
fatty acid elongase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

fatty acid elongase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

of very long chain fatty acids protein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
fatty acid elongase activity
fatty acid elongation, monounsaturated fatty acid
fatty acid elongation, polyunsaturated fatty acid
fatty acid elongation, saturated fatty acid
fatty acid metabolic process
lipid metabolic process
sphingolipid biosynthetic process
transferase activity
very long-chain fatty acid biosynthetic process

Displaying 1 entry
InterPro
ELO family

KEGG BRITE Database

Orthology

K10249

Name

elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]

References

20937905

Rhea

RHEA:32727

H⁺ + malonyl-CoA + a very-long-chain acyl-CoA

CO₂ + CoA + a very-long-chain 3-oxoacyl-CoA

Enzyme

2.3.1.199

PMID

Ortholog

Displaying entries **111 - 118** of **118** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Cervus canadensis	122422860	1574408_0:0039f6
Cervus elaphus	122685522	9860_0:004e79
Ursus americanus	123797477		URSAM04941
Phacochoerus africanus	125117488	41426_0:00095a
Budorcas taxicolor	128053469	37181_0:00228e
Moschus berezovskii	129561169	68408_0:003232
Bubalus kerabau	129619657	346063_0:002d58
Hippopotamus amphibius kiboko	130855289	575201_0:002351

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements