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malate dehydrogenase 1

Summary

Gene Symbol

MDH1

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 535182
KEGG Gene ID: bta:535182
PubChem: 535182

Annotation

Keyword

Acetylation
Cytoplasm
Methylation
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Tricarboxylic acid cycle
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3T145	Aromatic alpha-keto acid reductase Cytosolic malate dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
malate metabolic process	IEA	22301074 30032202
NADH metabolic process	IEA	30032202
oxaloacetate metabolic process	IEA	30032202
tricarboxylic acid cycle	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

primary metabolic process [inference]

tricarboxylic acid cycle

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

dicarboxylic acid metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NAD metabolic process [inference]

NADH metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IEA	30032202
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
L-malate dehydrogenase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

malate dehydrogenase activity [inference]

L-malate dehydrogenase activity

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

L-malate dehydrogenase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00025

Name

malate dehydrogenase [EC:1.1.1.37]

References

Rhea

RHEA:10780

(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD⁺

H⁺ + 3-(4-hydroxyphenyl)pyruvate + NADH

Enzyme

PMID

RHEA:21432

(S)-malate + NAD⁺

H⁺ + oxaloacetate + NADH

Enzyme

PMID

RHEA:20293

NAD⁺ + 3-(3,5-diiodo-4-hydroxyphenyl)lactate

H⁺ + NADH + 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate

Enzyme

1.1.1.96

PMID

3052244

Ortholog

Displaying entries **21 - 30** of **109** in total

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Oryzias latipes	100049475	ORYLA04760
Oreochromis niloticus	100711262	ORENI60506
Oreochromis niloticus	100711978	ORENI13146
Astatotilapia calliptera	113034741	ASTCA07864
Sparus aurata	115588220	SPAAU53735
Sparus aurata	115596971	SPAAU09721
Chrysemys picta bellii	101947638	CHRPI18120
Crocodylus porosus	109319553	CROPO07034
Pseudonaja textilis	113444209	PSETE16940
Anas platyrhynchos platyrhynchos	101794999	ANAPP00203

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External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements