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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pancreatic lipase
Summary
- Gene Symbol
-
- PNLIP
- Aliases
-
- PL
- triacylglycerol lipase
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lipid degradation
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P16233 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| intestinal cholesterol absorption | ||
| lipid metabolic process | ||
| positive regulation of triglyceride lipase activity | ||
| retinol metabolic process | ||
| lipid catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity | ||
| triglyceride lipase activity | ||
| metal ion binding | ||
| lipase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10602 | obsolete steatorrhea | |
| DOID:10607 | tropical sprue | |
| DOID:1588 | thrombocytopenia | |
| DOID:162 | cancer | |
| DOID:1793 | pancreatic cancer | |
| DOID:2913 | acute pancreatitis | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3620 | central nervous system cancer | |
| DOID:4905 | pancreatic carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0002570 | Steatorrhea |
| HP:0002630 | Fat malabsorption |
| HP:0003146 | Hypocholesterolemia |
| HP:0003623 | Neonatal onset |
| HP:0012236 | Elevated sweat chloride |
| Disease ID | Disease Name |
|---|---|
| OMIM:614338 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002016
- Gene Name
- pancreatic lipase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 116447337 | CORMO25136 | ||
| 103270000 | CARSF28287 | ||
| 115608307 | STRHB04697 |
