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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Rho guanine nucleotide exchange factor
Summary
- Gene Symbol
-
- Arhgef7
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Alternative splicing
- Cell junction
- Cell projection
- Coiled coil
- Cytoplasm
- Guanine-nucleotide releasing factor
- Neurogenesis
- Phosphoprotein
- Proteomics identification
- Reference proteome
- SH3 domain
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9ES28 |
|
| A0A0R4J0X8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of microtubule nucleation | ||
| lamellipodium assembly | ||
| Golgi organization | ||
| presynaptic actin cytoskeleton organization | ||
| positive regulation of protein binding |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| storage vacuole | ||
| growth cone | ||
| centrosome | ||
| cytosol | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| small GTPase binding | ||
| guanyl-nucleotide exchange factor activity | ||
| protein kinase binding | ||
| gamma-tubulin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- rho guanine nucleotide exchange factor 7
- Functional Category
-
- C: Energy production and conversion
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| lamellipodium assembly |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:6713 | cerebrovascular disease |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100145259 | Xenbase:XB-GENE-962606 | |||
| 100230434 | TAEGU11402 | |||
| 100402642 | CALJA20683 | |||
| 100447361 | PONAB06861 | |||
| 100516509 | PIGXX01537 | |||
| 100538686 | MELGA12411 | |||
| 100554940 | ANOCA04567 | |||
| 100607371 | NOMLE30811 | |||
| 100695420 | ORENI20872 | |||
| 100717780 | 10141_0:004417 | CAVPO02434 |
