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DNA polymerase delta 2, accessory subunit

Summary

Gene Symbol

POLD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

5425

PubChem

5425

Alliance of Genome Resources

HGNC:9176

Annotation

Keyword

3D-structure
Acetylation
DNA excision
DNA repair
DNA replication
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A087WWF6
P49005	DNA polymerase delta subunit p50

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
DNA replication	TAS	8530069
DNA-templated DNA replication	IDA	20334433
DNA strand elongation involved in DNA replication	IBA
error-prone translesion synthesis	IDA	24449906
DNA biosynthetic process	IDA	11595739

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

DNA strand elongation [inference]

DNA strand elongation involved in DNA replication

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

postreplication repair [inference]

translesion synthesis [inference]

error-prone translesion synthesis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	TAS	8530069
nucleoplasm	TAS
nucleoplasm	IDA
zeta DNA polymerase complex	IDA	22465957
zeta DNA polymerase complex	IPI	24449906

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

delta DNA polymerase complex

intracellular protein-containing complex [inference]

DNA polymerase complex [inference]

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

DNA polymerase complex [inference]

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
DNA binding	IEA
protein binding	IPI	12403614 15670210 16000169 16510448 26030842 26496610 28514442 31449058 33961781 38554706

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

DNA polymerase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
DNA strand elongation involved in DNA replication

Displaying **all 4** entries
InterPro
DNA polymerase alpha/delta/epsilon, subunit B
DNA polymerase delta subunit 2, C-terminal domain
DNA polymerase delta subunit, OB-fold domain
DNA polymerase delta/II small subunit family

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	5425	Xenbase:XB-GENE-999387
Mus musculus	18972	Xenbase:XB-GENE-999387	MOUSE06770
Bos taurus	281991		BOVIN28264
Rattus norvegicus	289758		RATNO08917
Pan troglodytes	472654		PANTR40141
Canis lupus familiaris	482686		CANLF20571
Macaca mulatta	700100		MACMU33172
Danio rerio	796456		DANRE42642
Monodelphis domestica	100030097		MONDO08719
Ornithorhynchus anatinus	100091173		ORNAN02017

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

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OrthoDB (Group)

International Collaboration

Acknowledgements