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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
neuroligin 3
Summary
- Gene Symbol
-
- NLGN3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Asperger syndrome
- Autism
- Cell adhesion
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Signal
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q4G160 |
|
| X5D2P6 |
|
| Q6MZK0 |
|
| X5D7L6 |
|
| Q9NZ94 |
|
| X5DNV3 |
|
| A0A8I5KSB7 |
|
| B7Z3P8 |
|
| A0A8I5QJH8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of excitatory postsynaptic potential | ||
| synapse assembly | ||
| positive regulation of synaptic transmission, glutamatergic | ||
| adult behavior | ||
| presynapse assembly |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane | ||
| endocytic vesicle | ||
| presynapse | ||
| postsynaptic specialization membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| neurexin family protein binding | ||
| signaling receptor activity | ||
| scaffold protein binding | ||
| cell adhesion molecule binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- carboxylesterase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase, type B |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:11446 | sciatic neuropathy | |
| DOID:12849 | autistic disorder |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 33962 | FB:FBgn0031866 | |||
| 40912 | FB:FBgn0083963 | |||
| 40913 | FB:FBgn0051146 | |||
| 42402 | FB:FBgn0083975 | |||
| 171297 | RGD:621119 | RATNO45435 | ||
| 181484 | WB:WBGene00006412 | |||
| 245537 | MGI:2444609 | MOUSE66654 | ||
| 447240 | Xenbase:XB-GENE-977264 | |||
| 473660 | 9598_0:005708 | PANTR46245 | ||
| 491947 | CANLF19872 |
