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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
UDP glucuronosyltransferase family 1 member A6
Summary
- Gene Symbol
-
- UGT1A6
- Aliases
-
- GNT1
- HLUGP
- UGT1F
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Endoplasmic reticulum
- Glycoprotein
- Glycosyltransferase
- Microsome
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of fatty acid metabolic process |
|
|
| negative regulation of glucuronosyltransferase activity |
|
|
| cellular glucuronidation | ||
| negative regulation of cellular glucuronidation |
|
|
| xenobiotic metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| enzyme binding | ||
| protein homodimerization activity | ||
| retinoic acid binding | ||
| protein heterodimerization activity | ||
| glucuronosyltransferase activity |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050590 | severe congenital neutropenia | |
| DOID:0060262 | gallbladder disease | |
| DOID:0060319 | cardiac arrest | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:0080525 | differentiated thyroid gland carcinoma | |
| DOID:0110029 | alpha thalassemia-intellectual disability syndrome type 1 | |
| DOID:0110030 | alpha thalassemia-X-linked intellectual disability syndrome | |
| DOID:0110031 | hemoglobin H disease | |
| DOID:0110845 | xeroderma pigmentosum group D |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002941
- Gene Name
- UDP glucuronosyltransferase 1 family, polypeptide A6
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 185500 | WB:WBGene00018206 | ||
| 35105 | FB:FBgn0032684 | ||
| 35139 | FB:FBgn0027070 | ||
| 35307 | FB:FBgn0026756 | ||
| 40079 | FB:FBgn0036842 | ||
| 41333 | FB:FBgn0026314 | ||
| 41334 | FB:FBgn0026315 | ||
| 41574 | FB:FBgn0038083 | ||
| 42774 | FB:FBgn0039085 | ||
| 42775 | FB:FBgn0039086 |
