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ATRX chromatin remodeler

Summary

Gene Symbol

ATRX

Organism

Homo sapiens (human)

External Links

NCBI Gene

546

PubChem

546

Alliance of Genome Resources

HGNC:886

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Chromatin regulator
DNA repair
DNA-binding
Disease variant
Helicase
Hydrolase
Intellectual disability
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Reference proteome
Telomere
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P46100	ATP-dependent helicase ATRX X-linked helicase II X-linked nuclear protein Znf-HX
A4LAA3	ATP-dependent helicase ATRX X-linked nuclear protein
B4DLW1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
DNA damage response, signal transduction by p53 class mediator	ISS
Sertoli cell development	IEA
positive regulation of telomere maintenance	ISS
replication fork processing	IBA ISS
protein localization to chromosome, telomeric region	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

cell cycle process [inference]

spindle organization [inference]

meiotic spindle organization

meiotic cell cycle process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to hydroxyurea

cellular response to nitrogen compound [inference]

cellular response to hydroxyurea

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization

chromosome organization [inference]

chromosome organization involved in meiotic cell cycle

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-DNA complex assembly [inference]

nucleosome assembly

protein-DNA complex organization [inference]

chromatin organization

chromatin remodeling

nucleosome organization [inference]

nucleosome assembly

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

heterochromatin organization [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

protein-DNA complex assembly [inference]

nucleosome assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

reproductive structure development [inference]

seminiferous tubule development

Sertoli cell development

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

meiotic cell cycle process [inference]

multicellular organismal process [inference]

multicellular organism growth

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

reproductive structure development [inference]

seminiferous tubule development

Sertoli cell development

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

post-embryonic appendage morphogenesis [inference]

post-embryonic limb morphogenesis [inference]

post-embryonic forelimb morphogenesis

appendage morphogenesis [inference]

limb morphogenesis [inference]

post-embryonic limb morphogenesis [inference]

post-embryonic forelimb morphogenesis

forelimb morphogenesis [inference]

post-embryonic forelimb morphogenesis

post-embryonic appendage morphogenesis [inference]

post-embryonic limb morphogenesis [inference]

post-embryonic forelimb morphogenesis

anatomical structure development [inference]

forebrain development

tube development [inference]

seminiferous tubule development

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

reproductive structure development [inference]

seminiferous tubule development

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

Sertoli cell development

growth [inference]

developmental growth [inference]

multicellular organism growth

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

response to chemical [inference]

response to organic substance [inference]

response to hydroxyurea [inference]

cellular response to hydroxyurea

response to inorganic substance [inference]

cellular response to inorganic substance [inference]

cellular response to hydroxyurea

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to hydroxyurea

cellular response to nitrogen compound [inference]

cellular response to hydroxyurea

response to nitrogen compound [inference]

response to hydroxyurea [inference]

cellular response to hydroxyurea

cellular response to nitrogen compound [inference]

cellular response to hydroxyurea

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to hydroxyurea

cellular response to nitrogen compound [inference]

cellular response to hydroxyurea

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of DNA metabolic process [inference]

regulation of DNA replication [inference]

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of DNA-templated DNA replication [inference]

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of DNA replication [inference]

positive regulation of DNA-templated DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

subtelomeric heterochromatin formation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of chromosome organization [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of maintenance of mitotic sister chromatid cohesion, telomeric [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of telomere maintenance [inference]

positive regulation of telomere maintenance

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of sister chromatid cohesion [inference]

regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of maintenance of mitotic sister chromatid cohesion, telomeric [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

regulation of nuclear cell cycle DNA replication [inference]

positive regulation of nuclear cell cycle DNA replication

positive regulation of cell cycle process [inference]

positive regulation of nuclear cell cycle DNA replication

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of sister chromatid cohesion [inference]

negative regulation of maintenance of sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion [inference]

negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of nuclear cell cycle DNA replication

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
heterochromatin	TAS	10570185
pericentric heterochromatin	IBA ISS
nuclear chromosome	IEA
chromosome, telomeric region	ISS
PML body	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin [inference]

heterochromatin

pericentric heterochromatin

cellular anatomical entity [inference]

nucleoplasm

nuclear body

PML body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome [inference]

nuclear chromosome

chromosomal region [inference]

chromosome, centromeric region [inference]

condensed chromosome, centromeric region

chromosome, telomeric region

chromosome, subtelomeric region

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10699177 12953102 17296936 22102817 22391447 24651726 24981860 25417162 26373281 26496610 27029610 33961781
ATP-dependent chromatin remodeler activity	IEA
chromatin binding	IDA	27029610
helicase activity	IEA
ATP hydrolysis activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

binding [inference]

protein binding

protein domain specific binding [inference]

chromo shadow domain binding

histone binding

methylated histone binding

modification-dependent protein binding [inference]

methylation-dependent protein binding [inference]

methylated histone binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

chromatin binding

chromatin DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

chromatin DNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity

ATP-dependent activity, acting on DNA [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Helicase

Functional Category

I: Lipid transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
hydrolase activity
nucleotide binding

Displaying **all 7** entries
InterPro
ATPase ARIP4-like
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
P-loop containing nucleoside triphosphate hydrolase
SNF2, N-terminal
SNF2-like, N-terminal domain superfamily
SNF2/RAD5-like, C-terminal helicase domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 13 in total

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DO ID	Disease Name	Source
DOID:1059	intellectual disability	Alliance of Genome Resources
DOID:0080982	X-linked mental retardation-hypotonic facies syndrome-1	Alliance of Genome Resources
DOID:0110030	alpha thalassemia-X-linked intellectual disability syndrome	Alliance of Genome Resources
DOID:0112125	alpha-thalassemia myelodysplasia syndrome	Alliance of Genome Resources
DOID:1115	sarcoma	Alliance of Genome Resources
DOID:1799	islet cell tumor	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:3068	glioblastoma	Alliance of Genome Resources
DOID:3069	malignant astrocytoma	Alliance of Genome Resources
DOID:3070	high grade glioma	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	22589		MGI:103067	MOUSE64669
Drosophila melanogaster	43080		FB:FBgn0039338
Caenorhabditis elegans	172077		WB:WBGene00006961
Rattus norvegicus	246284		RGD:619795	RATNO44991
Danio rerio	323299		ZFIN:ZDB-GENE-030912-11	DANRE07385
Pan troglodytes	449625	9598_0:0055f2
Canis lupus familiaris	480963			CANLF19910
Bos taurus	514473			BOVIN36845
Danio rerio	568580		ZFIN:ZDB-GENE-030131-2019
Macaca mulatta	705735			MACMU47854

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