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peroxisome proliferator activated receptor alpha
Summary
- Gene Symbol
-
- PPARA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Biological rhythms
- DNA-binding
- Lipid-binding
- Nucleus
- Receptor
- Reference proteome
- Transcription regulation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fatty acid metabolic process | ||
| negative regulation of signaling receptor activity | ||
| negative regulation of cytokine production involved in inflammatory response | ||
| response to hypoxia | ||
| cellular response to starvation |
GO Hierarchy
- regulation of circadian rhythm
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipid binding | ||
| nuclear steroid receptor activity | ||
| DNA-binding transcription repressor activity, RNA polymerase II-specific | ||
| DNA-binding transcription factor activity, RNA polymerase II-specific | ||
| DNA-binding transcription factor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:10908 | hydrocephalus | |
| DOID:12351 | alcoholic hepatitis | |
| DOID:1485 | cystic fibrosis | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:3393 | coronary artery disease | |
| DOID:5419 | schizophrenia | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 118901898 | BALMU04555 | ||
| 100657770 | LOXAF03234 | ||
| 100049840 | HORSE25995 | ||
| 397239 | PIGXX24910 | ||
| 281992 | BOVIN30877 | ||
| 100861393 | CAPHI25900 | ||
| 443457 | SHEEP15205 | ||
| 100356422 | RABIT17570 | ||
| 105992732 | DIPOR18791 | ||
| 100758990 | CRIGR24252 |
