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peroxisome proliferator activated receptor alpha
Summary
- Gene Symbol
-
- PPARA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative splicing
- Biological rhythms
- DNA-binding
- Lipid-binding
- Nucleus
- Receptor
- Reference proteome
- Transcription regulation
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of fatty acid metabolic process | ||
| negative regulation of signaling receptor activity | ||
| negative regulation of cytokine production involved in inflammatory response | ||
| response to hypoxia | ||
| cellular response to starvation |
GO Hierarchy
- regulation of circadian rhythm
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of signaling [inference]
regulation of growth [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II-specific DNA-binding transcription factor binding | ||
| DNA binding | ||
| DNA-binding transcription factor activity | ||
| nuclear receptor activity | ||
| DNA-binding transcription activator activity, RNA polymerase II-specific |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:10908 | hydrocephalus | |
| DOID:12351 | alcoholic hepatitis | |
| DOID:1485 | cystic fibrosis | |
| DOID:3146 | lipid metabolism disorder | |
| DOID:3393 | coronary artery disease | |
| DOID:5419 | schizophrenia | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100076848 | ORNAN05632 | ||
| 100917093 | SARHA04309 | ||
| 100415661 | CALJA19202 | ||
| 105586920 | CERAT33574 | ||
| 102133372 | MACFA00107 | ||
| 613250 | MACMU02564 | ||
| 105489798 | MACNE38902 | ||
| 101011461 | PAPAN12817 | ||
| 101146658 | GORGO24396 | ||
| 100975411 | PANPA24083 |
